产品: PRDM12 抗体
货号: DF3435
描述: Rabbit polyclonal antibody to PRDM12
应用: WB IF/ICC
反应: Human, Mouse
预测: Pig, Bovine, Rabbit, Dog, Chicken
分子量: 40 KD; 40kD(Calculated).
蛋白号: Q9H4Q4
RRID: AB_2835735

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 50ul RMB¥ 1250 现货
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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
预测:
Pig(100%), Bovine(100%), Rabbit(100%), Dog(100%), Chicken(100%)
克隆:
Polyclonal
特异性:
PRDM12 Antibody detects endogenous levels of total PRDM12.
RRID:
AB_2835735
引用格式: Affinity Biosciences Cat# DF3435, RRID:AB_2835735.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Gm998; PFM 9; PFM9; PR domain containing 12; PR domain containing protein 12; PR domain zinc finger protein 12; PR domain-containing protein 12; PRD12_HUMAN; PRDM 12; PRDM12;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q9H4Q4 PRD12_HUMAN:

Not found in adult tissues except in dorsal root ganglia.

序列:
MMGSVLPAEALVLKTGLKAPGLALAEVITSDILHSFLYGRWRNVLGEQLFEDKSHHASPKTAFTAEVLAQSFSGEVQKLSSLVLPAEVIIAQSSIPGEGLGIFSKTWIKAGTEMGPFTGRVIAPEHVDICKNNNLMWEVFNEDGTVRYFIDASQEDHRSWMTYIKCARNEQEQNLEVVQIGTSIFYKAIEMIPPDQELLVWYGNSHNTFLGIPGVPGLEEDQKKNKHEDFHPADSAAGPAGRMRCVICHRGFNSRSNLRSHMRIHTLDKPFVCRFCNRRFSQSSTLRNHVRLHTGERPYKCQVCQSAYSQLAGLRAHQKSARHRPPSTALQAHSPALPAPHAHAPALAAAAAAAAAAAAHHLPAMVL

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
100
Bovine
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
75
Horse
0
Sheep
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9H4Q4 作为底物

Site PTM Type Enzyme
S159 Phosphorylation
R259 Methylation
S260 Phosphorylation
R263 Methylation
K269 Acetylation
K269 Methylation
T294 Phosphorylation

研究背景

功能:

Involved in the positive regulation of histone H3-K9 dimethylation.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Not found in adult tissues except in dorsal root ganglia.

蛋白家族:

Belongs to the class V-like SAM-binding methyltransferase superfamily.

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