DLX4 Antibody - #DF3387

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产品: DLX4 抗体
货号: DF3387
描述: Rabbit polyclonal antibody to DLX4
应用: WB IF/ICC
反应: Human
预测: Bovine, Sheep, Dog
分子量: 34 KD; 26kD(Calculated).
蛋白号: Q92988
RRID: AB_2835769

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
预测:
Bovine(88%), Sheep(88%), Dog(88%)
克隆:
Polyclonal
特异性:
DLX4 Antibody detects endogenous levels of total DLX4.
RRID:
AB_2835769
引用格式: Affinity Biosciences Cat# DF3387, RRID:AB_2835769.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Beta protein 1; BP1; Distal less homeo box 7; Distal less homeo box 9; distal-less homeobox 4; DLX4; DLX4_HUMAN; DLX7; DLX8; DLX9; Homeobox protein DLX-4; Homeobox protein DLX-7; Homeobox protein DLX-8; Homeobox protein DLX4;

抗原和靶标

免疫原:
Uniprot:

Q92988(DLX4_HUMAN) >>Visit HPA database.

基因/基因ID:
DLX4(1748)
表达:
Q92988 DLX4_HUMAN:

Expressed in leukemia cells and placenta. Also expressed in kidney and fetal liver.

序列:
MTSLPCPLPGRDASKAVFPDLAPVPSVAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQPLCGPAEHPQELEADSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAWYQHHSSDVLASPQMM

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Bovine
88
Sheep
88
Dog
88
Pig
0
Horse
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q92988 作为底物

Site PTM Type Enzyme
T2 Phosphorylation
S3 Phosphorylation
S14 Phosphorylation
S96 Phosphorylation
S198 Phosphorylation

研究背景

功能:

May play a role in determining the production of hemoglobin S. May act as a repressor. During embryonic development, plays a role in palatogenesis.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in leukemia cells and placenta. Also expressed in kidney and fetal liver.

蛋白家族:

Belongs to the distal-less homeobox family.

文献引用

1). Identification and validation of DLX4 as a prognostic and diagnostic biomarker for clear cell renal cell carcinoma. Oncology Letters, 2023 (PubMed: 36936018) [IF=2.9]

Application: IHC    Species: Human    Sample: ccRCC tissues

Figure 5. High expression levels of DLX4 in ccRCC tissues. (A and B) Reverse transcription-quantitative PCR revealed high expression levels of DLX4 mRNA in ccRCC tissues compared with normal adjacent tissue. (C and D) Immunohistochemistry showed high expression levels of DLX4 protein in ccRCC tissues compared with normal adjacent tissue. Scale bar for entire images and local magnification images were 100 and 50 µm, respectively. ccRCC, clear cell renal cell carcinoma; DLX, distal-less homeobox. **P

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