产品: IP3KC 抗体
货号: DF3397
描述: Rabbit polyclonal antibody to IP3KC
应用: WB IF/ICC
反应: Human
预测: Rabbit
分子量: 102 KD; 75kD(Calculated).
蛋白号: Q96DU7
RRID: AB_2835779

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 50ul RMB¥ 1250 现货
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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
预测:
Rabbit(82%)
克隆:
Polyclonal
特异性:
IP3KC Antibody detects endogenous levels of total IP3KC.
RRID:
AB_2835779
引用格式: Affinity Biosciences Cat# DF3397, RRID:AB_2835779.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

4; 5-trisphosphate 3-kinase C; Inositol 1; inositol 1,4,5 trisphosphate 3 kinase C; Inositol trisphosphate 3 kinase C; Inositol-trisphosphate 3-kinase C; InsP 3 kinase C; InsP 3-kinase C; IP3 3-kinase C; IP3 3KC; IP3K C; IP3KC; IP3KC_HUMAN; Itpkc;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q96DU7 IP3KC_HUMAN:

Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain.

序列:
MRRCPCRGSLNEAEAGALPAAARMGLEAPRGGRRRQPGQQRPGPGAGAPAGRPEGGGPWARTEGSSLHSEPERAGLGPAPGTESPQAEFWTDGQTEPAAAGLGVETERPKQKTEPDRSSLRTHLEWSWSELETTCLWTETGTDGLWTDPHRSDLQFQPEEASPWTQPGVHGPWTELETHGSQTQPERVKSWADNLWTHQNSSSLQTHPEGACPSKEPSADGSWKELYTDGSRTQQDIEGPWTEPYTDGSQKKQDTEAARKQPGTGGFQIQQDTDGSWTQPSTDGSQTAPGTDCLLGEPEDGPLEEPEPGELLTHLYSHLKCSPLCPVPRLIITPETPEPEAQPVGPPSRVEGGSGGFSSASSFDESEDDVVAGGGGASDPEDRSGSKPWKKLKTVLKYSPFVVSFRKHYPWVQLSGHAGNFQAGEDGRILKRFCQCEQRSLEQLMKDPLRPFVPAYYGMVLQDGQTFNQMEDLLADFEGPSIMDCKMGSRTYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQWRETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYVACLEELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLPWAEGNREDGYLWGLDNMICLLQGLAQS

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Rabbit
82
Pig
75
Dog
75
Bovine
58
Sheep
58
Horse
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q96DU7 作为底物

Site PTM Type Enzyme
R7 Methylation
S9 Phosphorylation
R30 Methylation
S84 Phosphorylation
S127 Phosphorylation
S190 Phosphorylation
K224 Ubiquitination
S322 Phosphorylation
T333 Phosphorylation
T336 Phosphorylation
S348 Phosphorylation
S378 Phosphorylation
Y398 Phosphorylation
S404 Phosphorylation
Y456 Phosphorylation
Y457 Phosphorylation
K499 Ubiquitination
T566 Phosphorylation
K569 Ubiquitination
K579 Ubiquitination

研究背景

功能:

Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate.

细胞定位:

Nucleus. Cytoplasm.
Note: Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain.

蛋白家族:

Belongs to the inositol phosphokinase (IPK) family.

研究领域

· Environmental Information Processing > Signal transduction > Calcium signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Phosphatidylinositol signaling system.

· Metabolism > Carbohydrate metabolism > Inositol phosphate metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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