产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3477, RRID:AB_2835840.
展开/折叠
CHETK; Chetk-beta; Chkb; Chkb choline kinase beta; Chkb protein; CHKB_HUMAN; CHKL; Choline kinase beta; Choline kinase-like; Choline kinase-like protein; Choline/ethanolamine kinase; choline/ethanolamine kinase beta; Choline/ethanolamine kinase, beta; CK; CK/EK; CK/EK-beta; CKB; CKEKB; EK; EKB; Ethanolamine kinase; Ethanolamine kinase beta; Ethanolamine kinase, beta; MDCMC;
抗原和靶标
- Q9Y259 CHKB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAEATAVAGSGAVGGCLAKDGLQQSKCPDTTPKRRRASSLSRDAERRAYQWCREYLGGAWRRVQPEELRVYPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTQELREPVLSAAIATKMAQFHGMEMPFTKEPHWLFGTMERYLKQIQDLPPTGLPEMNLLEMYSLKDEMGNLRKLLESTPSPVVFCHNDIQEGNILLLSEPENADSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKARPTDYPTQEQQLHFIRHYLAEAKKGETLSQEEQRKLEEDLLVEVSRYALASHFFWGLWSILQASMSTIEFGYLDYAQSRFQFYFQQKGQLTSVHSSS
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9Y259 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| S39 | Phosphorylation | Uniprot | |
| S40 | Phosphorylation | Uniprot | |
| S42 | Phosphorylation | Uniprot | |
| Y72 | Phosphorylation | Uniprot | |
| S75 | Phosphorylation | Uniprot | |
| S79 | Phosphorylation | Uniprot | |
| K321 | Ubiquitination | Uniprot | |
| Y381 | Phosphorylation | Uniprot | |
| S394 | Phosphorylation | Uniprot |
研究背景
Has a key role in phospholipid metabolism, and catalyzes the first step of phosphatidylethanolamine and phosphatidylcholine biosynthesis.
Homodimer, and heterodimer with CHKA.
Belongs to the choline/ethanolamine kinase family.
研究领域
· Human Diseases > Cancers: Overview > Choline metabolism in cancer. (View pathway)
· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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