ADRB2 Antibody - #DF3512

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产品: ADRB2 抗体
货号: DF3512
描述: Rabbit polyclonal antibody to ADRB2
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Rabbit
蛋白号: P07550
RRID: AB_2835874

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
ADRB2 Antibody detects endogenous levels of total ADRB2.
RRID:
AB_2835874
引用格式: Affinity Biosciences Cat# DF3512, RRID:AB_2835874.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ADRB2; ADRB2_HUMAN; ADRB2R; ADRBR; Adrenergic beta 2 receptor surface; Adrenoceptor beta 2 surface; B2AR; BAR; beta 2 adrenoceptor; Beta 2 adrenoreceptor; Beta-2 adrenergic receptor; Beta-2 adrenoceptor; Beta-2 adrenoreceptor; BETA2AR; Catecholamine receptor; OTTHUMP00000160386;

抗原和靶标

免疫原:

A synthesized peptide derived from human ADRB2, corresponding to a region within C-terminal amino acids.

基因/基因ID:
ADRB2(154)

研究领域

· Environmental Information Processing > Signal transduction > Calcium signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > cAMP signaling pathway.   (View pathway)

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

· Organismal Systems > Circulatory system > Adrenergic signaling in cardiomyocytes.   (View pathway)

· Organismal Systems > Endocrine system > Regulation of lipolysis in adipocytes.

· Organismal Systems > Endocrine system > Renin secretion.

· Organismal Systems > Digestive system > Salivary secretion.

文献引用

1). 16α-OHE1 alleviates hypoxia-induced inflammation and myocardial damage via the activation of β2-Adrenergic receptor. Molecular and cellular endocrinology (PubMed: 38518841) [IF=3.8]
2). Norepinephrine protects against cochlear outer hair cell damage and noise-induced hearing loss via α2A-adrenergic receptor. BMC neuroscience, 2024 (PubMed: 38291397) [IF=2.4]
3). A Novel Mechanism of 16α-OHE1, One of Estrogen Metabolites, Alleviating Inflammatory Infiltration in Hypoxia-Induced Myocardial Injury via β2-Adrenergic Receptor. Research Square, 2023

Application: WB    Species: Rat    Sample: H9C2 cells

Figure 6. 16α-OHE1 alleviates cardiomyocyte damage. (A-B) ELISA kits were used to measure creatine kinase isoenzyme (CK-MB) and troponin T (cTnT) levels in H9C2 cells. (C, D) Relative protein levels of brain natriuretic peptide (BNP) in H9C2 cells. (E, F) Relative protein levels of β2-adrenoceptor (β2AR) in H9C2 cells. (G-I) ELISA kits were used to measure interleukin 6 (IL-6), interleukin 1β (IL-1β), and tumor necrosis factor α (TNF-α) levels in H9C2 cells. (J) The viability of H9C2 cells exposed to hypoxia for 24 was assessed by CCK-8 assays. (K) Apoptosis in H9C2 cells incubated under hypoxic conditions for 24 h was evaluated by flow cytometry. n = 3. *p < 0.05, **p < 0.01 vs. N; #p < 0.05, ##p < 0.01 vs. H. The data were presented as the mean ± SEM. (one-way ANOVA)

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