| 产品: | Cytochrome P450 26C1 抗体 |
| 货号: | DF3570 |
| 描述: | Rabbit polyclonal antibody to Cytochrome P450 26C1 |
| 应用: | WB IHC |
| 反应: | Human, Mouse |
| 预测: | Pig, Bovine, Sheep, Rabbit |
| 分子量: | 0 KD; 57kD(Calculated). |
| 蛋白号: | Q6V0L0 |
| RRID: | AB_2835942 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3570, RRID:AB_2835942.
展开/折叠
CP26C_HUMAN; cyp26b1l; CYP26C1; cyp26d1; Cytochrome P450 26C1; Cytochrome P450 family 26 subfamily C polypeptide 1; Cytochrome P450, subfamily XXVIC polypeptide 1; EG546726; FFDD4; FLJ45301; MGC158120; retinoic acid catabolizing enzyme;
抗原和靶标
- Q6V0L0 CP26C_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFPWGLSCLSVLGAAGTALLCAGLLLSLAQHLWTLRWMLSRDRASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRRRRKVLARVFSRAALERYVPRLQGALRHEVRSWCAAGGPVSVYDASKALTFRMAARILLGLRLDEAQCATLARTFEQLVENLFSLPLDVPFSGLRKGIRARDQLHRHLEGAISEKLHEDKAAEPGDALDLIIHSARELGHEPSMQELKESAVELLFAAFFTTASASTSLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPDLSLAALGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATPAFPAMQTVPIVHPVDGLRLFFHPLTPSVAGNGLCL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q6V0L0 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y80 | Phosphorylation | Uniprot | |
| S150 | Phosphorylation | Uniprot | |
| T300 | Phosphorylation | Uniprot | |
| K321 | Ubiquitination | Uniprot |
研究背景
Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate).
Membrane>Single-pass membrane protein.
Detected in most tissues at very low level.
Belongs to the cytochrome P450 family.
研究领域
· Metabolism > Metabolism of cofactors and vitamins > Retinol metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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