| 产品: | RAD54 抗体 |
| 货号: | DF3631 |
| 描述: | Rabbit polyclonal antibody to RAD54 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 85 KD; 84kD(Calculated). |
| 蛋白号: | Q92698 |
| RRID: | AB_2836003 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3631, RRID:AB_2836003.
展开/折叠
DNA repair and recombination protein RAD54 like; DNA repair and recombination protein RAD54-like; hHR 54; hHR54; HR 54; HR54; hRAD 54; hRAD54; RAD 54A; RAD 54L; RAD54 (S. cerevisiae) like; RAD54 homolog; RAD54 like (S. cerevisiae); RAD54 like; RAD54 like protein; RAD54_HUMAN; RAD54A; RAD54L;
抗原和靶标
- Q92698 RAD54_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRRSLAPSQLAKRKPEGRSCDDEDWQPGLVTPRKRKSSSETQIQECFLSPFRKPLSQLTNQPPCLDSSQHEAFIRSILSKPFKVPIPNYQGPLGSRALGLKRAGVRRALHDPLEKDALVLYEPPPLSAHDQLKLDKEKLPVHVVVDPILSKVLRPHQREGVKFLWECVTSRRIPGSHGCIMADEMGLGKTLQCITLMWTLLRQSPECKPEIDKAVVVSPSSLVKNWYNEVGKWLGGRIQPLAIDGGSKDEIDQKLEGFMNQRGARVSSPILIISYETFRLHVGVLQKGSVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERLRELTSIVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPLQTELYKRFLRQAKPAEELLEGKMSVSSLSSITSLKKLCNHPALIYDKCVEEEDGFVGALDLFPPGYSSKALEPQLSGKMLVLDYILAVTRSRSSDKVVLVSNYTQTLDLFEKLCRARRYLYVRLDGTMSIKKRAKVVERFNSPSSPDFVFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYRLLSAGTIEEKIFQRQSHKKALSSCVVDEEQDVERHFSLGELKELFILDEASLSDTHDRLHCRRCVNSRQIRPPPDGSDCTSDLAGWNHCTDKWGLRDEVLQAAWDAASTAITFVFHQRSHEEQRGLR
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q92698 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S4 | Phosphorylation | Uniprot | |
| K12 | Acetylation | Uniprot | |
| T31 | Phosphorylation | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| S38 | Phosphorylation | Uniprot | |
| S39 | Phosphorylation | Uniprot | |
| T41 | Phosphorylation | Uniprot | |
| S49 | Phosphorylation | Uniprot | |
| K53 | Ubiquitination | Uniprot | |
| K83 | Ubiquitination | Uniprot | |
| K115 | Ubiquitination | Uniprot | |
| K133 | Ubiquitination | Uniprot | |
| K138 | Ubiquitination | Uniprot | |
| K224 | Ubiquitination | Uniprot | |
| K232 | Ubiquitination | Uniprot | |
| S247 | Phosphorylation | Uniprot | |
| K248 | Ubiquitination | Uniprot | |
| K254 | Ubiquitination | Uniprot | |
| K302 | Ubiquitination | Uniprot | |
| T308 | Phosphorylation | Uniprot | |
| Y309 | Phosphorylation | Uniprot | |
| S314 | Phosphorylation | Uniprot | |
| K355 | Ubiquitination | Uniprot | |
| K363 | Ubiquitination | Uniprot | |
| S386 | Phosphorylation | Uniprot | |
| K402 | Ubiquitination | Uniprot | |
| K407 | Ubiquitination | Uniprot | |
| K425 | Ubiquitination | Uniprot | |
| K432 | Ubiquitination | Uniprot | |
| K441 | Ubiquitination | Uniprot | |
| K454 | Ubiquitination | Uniprot | |
| K455 | Ubiquitination | Uniprot | |
| Y503 | Phosphorylation | Uniprot | |
| S572 | Phosphorylation | Uniprot | |
| K630 | Ubiquitination | Uniprot | |
| K639 | Ubiquitination | Uniprot | |
| K662 | Ubiquitination | Uniprot | |
| S671 | Phosphorylation | Uniprot |
研究背景
Involved in DNA repair and mitotic recombination. Functions in the recombinational DNA repair (RAD52) pathway. Dissociates RAD51 from nucleoprotein filaments formed on dsDNA. Could be involved in the turnover of RAD51 protein-dsDNA filaments (By similarity). May play also an essential role in telomere length maintenance and telomere capping in mammalian cells.
Nucleus.
Interacts (via N-terminus) with RAD51.
Belongs to the SNF2/RAD54 helicase family.
研究领域
· Genetic Information Processing > Replication and repair > Homologous recombination.
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