产品: MRPL14 抗体
货号: DF3659
描述: Rabbit polyclonal antibody to MRPL14
应用: WB IF/ICC
反应: Human, Mouse, Rat
预测: Zebrafish, Bovine, Horse, Sheep, Dog
分子量: 16 KD; 16kD(Calculated).
蛋白号: Q6P1L8
RRID: AB_2836031

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Zebrafish(83%), Bovine(83%), Horse(83%), Sheep(83%), Dog(83%)
克隆:
Polyclonal
特异性:
MRPL14 Antibody detects endogenous levels of total MRPL14.
RRID:
AB_2836031
引用格式: Affinity Biosciences Cat# DF3659, RRID:AB_2836031.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

1110006I11Rik; 39S ribosomal protein L14; 39S ribosomal protein L14 mitochondrial; 39S ribosomal protein L32; AI846816; L14mt; L32mt; mitochondrial; MRP L14; MRP L32; MRP-L14; MRP-L32; mrpl14; RM14_HUMAN;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
序列:
MAFFTGLWGPFTCVSRVLSHHCFSTTGSLSAIQKMTRVRVVDNSALGNSPYHRAPRCIHVYKKNGVGKVGDQILLAIKGQKKKALIVGHCMPGPRMTPRFDSNNVVLIEDNGNPVGTRIKTPIPTSLRKREGEYSKVLAIAQNFV

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Horse
83
Bovine
83
Sheep
83
Dog
83
Zebrafish
83
Pig
75
Xenopus
75
Chicken
67
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q6P1L8 作为底物

Site PTM Type Enzyme
S49 Phosphorylation
Y51 Phosphorylation
T121 Phosphorylation
T125 Phosphorylation

研究背景

功能:

Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (Probable).

细胞定位:

Mitochondrion.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Component of the mitochondrial large ribosomal subunit (mt-LSU). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins. Interacts with MALSU1.

蛋白家族:

Belongs to the universal ribosomal protein uL14 family.

研究领域

· Genetic Information Processing > Translation > Ribosome.

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