产品: | PGD 抗体 |
货号: | DF3714 |
描述: | Rabbit polyclonal antibody to PGD |
应用: | WB IF/ICC |
反应: | Human, Mouse, Rat |
预测: | Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
分子量: | 40 KD; 53kD(Calculated). |
蛋白号: | P52209 |
RRID: | AB_2836078 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3714, RRID:AB_2836078.
展开/折叠
0610042A05Rik; 6 phosphogluconate dehydrogenase, decarboxylating; 6-phosphogluconate dehydrogenase; 6PGD; 6PGD_HUMAN; AU019875; C78335; decarboxylating; OTTMUSP00000011754; Pgd; Phosphogluconate dehydrogenase; RP23-249G3.4;
抗原和靶标
A synthesized peptide derived from human PGD, corresponding to a region within C-terminal amino acids.
- P52209 6PGD_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSSYNA
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P52209 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
K38 | Acetylation | Uniprot | |
K38 | Ubiquitination | Uniprot | |
K48 | Ubiquitination | Uniprot | |
K51 | Ubiquitination | Uniprot | |
S57 | Phosphorylation | Uniprot | |
K59 | Acetylation | Uniprot | |
K59 | Ubiquitination | Uniprot | |
K76 | Acetylation | Uniprot | |
S104 | Phosphorylation | Uniprot | |
Y106 | Phosphorylation | Uniprot | |
K119 | Ubiquitination | Uniprot | |
S126 | Phosphorylation | Uniprot | |
S129 | Phosphorylation | Uniprot | |
K147 | Acetylation | Uniprot | |
K147 | Ubiquitination | Uniprot | |
K154 | Acetylation | Uniprot | |
K154 | Ubiquitination | Uniprot | |
K163 | Ubiquitination | Uniprot | |
T166 | Phosphorylation | Uniprot | |
K184 | Ubiquitination | Uniprot | |
K248 | Acetylation | Uniprot | |
K248 | Ubiquitination | Uniprot | |
K253 | Ubiquitination | Uniprot | |
S257 | Phosphorylation | Uniprot | |
K261 | Ubiquitination | Uniprot | |
K265 | Ubiquitination | Uniprot | |
K294 | Acetylation | Uniprot | |
K294 | Ubiquitination | Uniprot | |
K309 | Acetylation | Uniprot | |
K309 | Ubiquitination | Uniprot | |
K316 | Acetylation | Uniprot | |
K316 | Ubiquitination | Uniprot | |
K317 | Ubiquitination | Uniprot | |
S318 | Phosphorylation | Uniprot | |
R324 | Methylation | Uniprot | |
K377 | Ubiquitination | Uniprot | |
K460 | Ubiquitination | Uniprot | |
T475 | Phosphorylation | Uniprot | |
S479 | Phosphorylation | Uniprot | |
S480 | Phosphorylation | Uniprot | |
Y481 | Phosphorylation | Uniprot |
研究背景
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
Cytoplasm.
Homodimer.
Belongs to the 6-phosphogluconate dehydrogenase family.
研究领域
· Metabolism > Carbohydrate metabolism > Pentose phosphate pathway.
· Metabolism > Metabolism of other amino acids > Glutathione metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > Carbon metabolism.
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