产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3715, RRID:AB_2836079.
展开/折叠
6 phosphogluconolactonase; 6PGL;
抗原和靶标
A synthesized peptide derived from human PGLS, corresponding to a region within C-terminal amino acids.
- O95336 6PGL_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGARARFALGLSGGSLVSMLARELPAAVAPAGPASLARWTLGFCDERLVPFDHAESTYGLYRTHLLSRLPIPESQVITINPELPVEEAAEDYAKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O95336 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| S46 | Phosphorylation | Uniprot | |
| S49 | Phosphorylation | Uniprot | |
| R81 | Methylation | Uniprot | |
| T91 | Phosphorylation | Uniprot | |
| Y92 | Phosphorylation | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| S178 | Phosphorylation | Uniprot | |
| K180 | Acetylation | Uniprot | |
| T204 | Phosphorylation | Uniprot | |
| K235 | Ubiquitination | Uniprot | |
| T249 | Phosphorylation | Uniprot | |
| K254 | Ubiquitination | Uniprot | |
| T257 | Phosphorylation | Uniprot |
研究背景
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
Cytoplasm.
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
研究领域
· Metabolism > Carbohydrate metabolism > Pentose phosphate pathway.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > Carbon metabolism.
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