| 产品: | ANP32B 抗体 |
| 货号: | DF3730 |
| 描述: | Rabbit polyclonal antibody to ANP32B |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat, Monkey |
| 预测: | Zebrafish, Bovine, Horse, Sheep, Dog |
| 分子量: | 29 KD; 29kD(Calculated). |
| 蛋白号: | Q92688 |
| RRID: | AB_2836094 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3730, RRID:AB_2836094.
展开/折叠
Acidic (leucine rich) nuclear phosphoprotein 32 family member B; Acidic leucine rich nuclear phosphoprotein 32 family member B; Acidic leucine-rich nuclear phosphoprotein 32 family member B; Acidic nuclear phosphoprotein 32 family member B; Acidic protein rich in leucines; AN32B_HUMAN; ANP 32B; ANP32B; APRIL; OTTHUMP0000006377; PAL 31; PAL31; PHAPI 2; PHAPI2; PHAPI2 protein; PHAPI2a; Proliferation related acidic leucine rich protein; Putative HLA-DR-associated protein I-2; Silver stainable protein SSP 29; Silver stainable protein SSP29; Silver-stainable protein SSP29; Ssp 29; Ssp29;
抗原和靶标
- Q92688 AN32B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDMKRRIHLELRNRTPAAVRELVLDNCKSNDGKIEGLTAEFVNLEFLSLINVGLISVSNLPKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNLSGNKLKDISTLEPLKKLECLKSLDLFNCEVTNLNDYRESVFKLLPQLTYLDGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q92688 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R12 | Methylation | Uniprot | |
| T15 | Phosphorylation | Uniprot | |
| C27 | S-Nitrosylation | Uniprot | |
| K33 | Acetylation | Uniprot | |
| K67 | Ubiquitination | Uniprot | |
| K68 | Sumoylation | Uniprot | |
| K68 | Ubiquitination | Uniprot | |
| R75 | Methylation | Uniprot | |
| K86 | Acetylation | Uniprot | |
| K86 | Ubiquitination | Uniprot | |
| S96 | Phosphorylation | Uniprot | |
| K99 | Acetylation | Uniprot | |
| K99 | Ubiquitination | Uniprot | |
| K101 | Acetylation | Uniprot | |
| K101 | Ubiquitination | Uniprot | |
| S104 | Phosphorylation | Uniprot | |
| K110 | Acetylation | Uniprot | |
| K116 | Acetylation | Uniprot | |
| K116 | Ubiquitination | Uniprot | |
| S117 | Phosphorylation | Uniprot | |
| T126 | Phosphorylation | Uniprot | |
| K137 | Ubiquitination | Uniprot | |
| Y148 | Phosphorylation | Uniprot | |
| S158 | Phosphorylation | Uniprot | |
| K236 | Acetylation | Uniprot | |
| K239 | Acetylation | Uniprot | |
| T244 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
研究背景
Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.
Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group (By similarity).
Nucleus.
Note: Accumulates in the nuclei at the S phase.
Cytoplasm.
Note: Lacks a nuclear localization signal.
Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.
Monomer. Interacts with histones H3 and H4.
Histone binding is mediated by the concave surface of the LRR region.
Belongs to the ANP32 family.
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