产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3733, RRID:AB_2836097.
展开/折叠
ACH2; Acyl CoA thioesterase 1, cytosolic; Acyl coenzyme A thioesterase 1; CTE 1; CTE I; CTE Ib; Cte1; Cytosolic acyl CoA thioesterase 1; D12Ucla1; Inducible cytosolic acyl-coenzyme A thioester hydrolase; Long chain acyl CoA hydrolase; Long chain acyl CoA thioester hydrolase;
抗原和靶标
- Q86TX2 ACOT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLGELDLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRTPLAVELEVLDGHDPDPGRLLCRVRHERYFLPPGVRREPVRAGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAVNYLLSHPEVKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLRYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGHYIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIPSKV
翻译修饰 - Q86TX2 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R24 | Methylation | Uniprot | |
| K42 | Acetylation | Uniprot | |
| T56 | Phosphorylation | Uniprot | |
| T100 | Phosphorylation | Uniprot | |
| S232 | Phosphorylation | Uniprot | |
| S257 | Phosphorylation | Uniprot | |
| K286 | Ubiquitination | Uniprot | |
| Y289 | Phosphorylation | Uniprot | |
| K306 | Ubiquitination | Uniprot | |
| K340 | Acetylation | Uniprot | |
| K400 | Acetylation | Uniprot | |
| K420 | Ubiquitination | Uniprot |
研究背景
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating intracellular levels of acyl-CoAs, free fatty acids and CoASH. More active towards saturated and unsaturated long chain fatty acyl-CoAs (C12-C20).
Cytoplasm>Cytosol.
Monomer.
Belongs to the C/M/P thioester hydrolase family.
研究领域
· Metabolism > Lipid metabolism > Fatty acid elongation.
· Metabolism > Lipid metabolism > Biosynthesis of unsaturated fatty acids.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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