产品: SLC25A31 抗体
货号: DF3743
描述: Rabbit polyclonal antibody to SLC25A31
应用: WB IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 35 KD; 35kD(Calculated).
蛋白号: Q9H0C2
RRID: AB_2836107

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
克隆:
Polyclonal
特异性:
SLC25A31 Antibody detects endogenous levels of total SLC25A31.
RRID:
AB_2836107
引用格式: Affinity Biosciences Cat# DF3743, RRID:AB_2836107.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

AAC4; Adenine nucleotide translocator 4; ADP; ADP,ATP carrier protein 4; ADP/ATP translocase 4; ADT4_HUMAN; ANT 4; ANT4; ATP carrier protein 4; SFEC; Slc25a31; Solute carrier family 25 member 31; Sperm flagellar energy carrier protein;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q9H0C2 ADT4_HUMAN:

Expressed in brain, liver, sperm and testis.

序列:
MHREPAKKKAEKRLFDASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVLYDKIKEFFHIDIGGR

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9H0C2 作为底物

Site PTM Type Enzyme
S34 Phosphorylation
T36 Phosphorylation
S58 Phosphorylation
Y63 Phosphorylation
Y93 Phosphorylation
T96 Phosphorylation
K104 Acetylation
K104 Ubiquitination
K106 Acetylation
K106 Ubiquitination
S113 Phosphorylation
K117 Ubiquitination
K218 Acetylation
K219 Acetylation
Y261 Phosphorylation
T264 Phosphorylation

研究背景

功能:

Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility.

细胞定位:

Mitochondrion inner membrane>Multi-pass membrane protein. Cell projection>Cilium>Flagellum.
Note: In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in brain, liver, sperm and testis.

蛋白家族:

The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue.

Belongs to the mitochondrial carrier (TC 2.A.29) family.

研究领域

· Cellular Processes > Cell growth and death > Necroptosis.   (View pathway)

· Cellular Processes > Cell growth and death > Cellular senescence.   (View pathway)

· Environmental Information Processing > Signal transduction > Calcium signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway.   (View pathway)

· Human Diseases > Neurodegenerative diseases > Parkinson's disease.

· Human Diseases > Neurodegenerative diseases > Huntington's disease.

· Human Diseases > Infectious diseases: Viral > HTLV-I infection.

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