产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3750, RRID:AB_2836114.
展开/折叠
2900006B13Rik; 5-phosphohydroxy-L-lysine phospho-lyase; Alanine glyoxylate aminotransferase 2 like 2; MGC117348; MGC15875; MGC45484; OTTMUSP00000005767; PHLU; PP9286; RP23-79E13.3;
抗原和靶标
- Q8IUZ5 AT2L2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAADQRPKADTLALRQRLISSSCRLFFPEDPVKIVRAQGQYMYDEQGAEYIDCISNVAHVGHCHPLVVQAAHEQNQVLNTNSRYLHDNIVDYAQRLSETLPEQLCVFYFLNSGSEANDLALRLARHYTGHQDVVVLDHAYHGHLSSLIDISPYKFRNLDGQKEWVHVAPLPDTYRGPYREDHPNPAMAYANEVKRVVSSAQEKGRKIAAFFAESLPSVGGQIIPPAGYFSQVAEHIRKAGGVFVADEIQVGFGRVGKHFWAFQLQGKDFVPDIVTMGKSIGNGHPVACVAATQPVARAFEATGVEYFNTFGGSPVSCAVGLAVLNVLEKEQLQDHATSVGSFLMQLLGQQKIKHPIVGDVRGVGLFIGVDLIKDEATRTPATEEAAYLVSRLKENYVLLSTDGPGRNILKFKPPMCFSLDNARQVVAKLDAILTDMEEKVRSCETLRLQP
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q8IUZ5 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
K8 | Ubiquitination | Uniprot | |
S20 | Phosphorylation | Uniprot | |
K33 | Acetylation | Uniprot | |
K33 | Ubiquitination | Uniprot | |
Y153 | Phosphorylation | Uniprot | |
K162 | Ubiquitination | Uniprot | |
K278 | Ubiquitination | Uniprot | |
K353 | Ubiquitination | Uniprot | |
K393 | Ubiquitination | Uniprot | |
K439 | Ubiquitination | Uniprot |
研究背景
Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde.
Mitochondrion.
Homotetramer.
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
研究领域
· Metabolism > Amino acid metabolism > Lysine degradation.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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