AKR1CL2 Antibody - #DF3758

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产品: AKR1CL2 抗体
货号: DF3758
描述: Rabbit polyclonal antibody to AKR1CL2
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 37 KD; 37kD(Calculated).
蛋白号: Q96JD6
RRID: AB_2836122

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(92%), Rabbit(100%), Dog(85%)
克隆:
Polyclonal
特异性:
AKR1CL2 Antibody detects endogenous levels of total AKR1CL2.
RRID:
AB_2836122
引用格式: Affinity Biosciences Cat# DF3758, RRID:AB_2836122.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

1; 1,5-anhydro-D-fructose reductase; 5-anhydro-D-fructose reductase; AF reductase; AKCL2_HUMAN; AKR1CL2; Akr1e2; AKRDC1; Aldo keto reductase family 1 member C like protein 2; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member E2; HTSP; LoopADR; Testis specific protein; Testis-specific protein;

抗原和靶标

免疫原:
Uniprot:

Q96JD6(AKCL2_HUMAN) >>Visit HPA database.

基因/基因ID:
AKR1E2(83592)
表达:
Q96JD6 AKCL2_HUMAN:

Specifically expressed in testis (PubMed:12604216, PubMed:15118078). Expressed in testicular germ cells and testis interstitial cells (PubMed:15118078).

序列:
MGDIPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNHKDYPFHIEY

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Rabbit
100
Sheep
92
Dog
85
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q96JD6 作为底物

Site PTM Type Enzyme
K183 Ubiquitination
T218 Phosphorylation

研究背景

功能:

Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol (By similarity). Has low NADPH-dependent reductase activity towards 9,10-phenanthrenequinone (in vitro).

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Specifically expressed in testis. Expressed in testicular germ cells and testis interstitial cells.

亚基结构:

Monomer.

蛋白家族:

Belongs to the aldo/keto reductase family.

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