| 产品: | AASS 抗体 |
| 货号: | DF3763 |
| 描述: | Rabbit polyclonal antibody to AASS |
| 应用: | WB IF/ICC |
| 反应: | Human, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 102 KD; 102kD(Calculated). |
| 蛋白号: | Q9UDR5 |
| RRID: | AB_2836127 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3763, RRID:AB_2836127.
展开/折叠
Alpha aminoadipic semialdehyde synthase mitochondrial; LKR; LKR/SDH; LKRSDH; LOR; LORSDH; Lysine ketoglutarate reductase; Saccharopine dehydrogenase; SDH;
抗原和靶标
- Q9UDR5 AASS_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQPSNRRAIHDKDYVKAGGILQEDISEACLILGVKRPPEEKLMSRKTYAFFSHTIKAQEANMGLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAGMINILHGMGLRLLALGHHTPFMHIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPCEYVEPHELKEVSQTGDLRKVYGTVLSRHHHLVRKTDAVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAGVEGCPALPHKLVAICDISADTGGSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLYPYVEEMILSDATQPLESQNFSPVVRDAVITSNGTLPDKYKYIQTLRESRERAQSLSMGTRRKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLDHMLAMETIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGISSAHTLLRGTLRYKGYMKALNGFVKLGLINREALPAFRPEANPLTWKQLLCDLVGISPSSEHDVLKEAVLKKLGGDNTQLEAAEWLGLLGDEQVPQAESILDALSKHLVMKLSYGPEEKDMIVMRDSFGIRHPSGHLEHKTIDLVAYGDINGFSAMAKTVGLPTAMAAKMLLDGEIGAKGLMGPFSKEIYGPILERIKAEGIIYTTQSTIKP
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9UDR5 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T51 | Phosphorylation | Uniprot | |
| Y55 | Phosphorylation | Uniprot | |
| K212 | Acetylation | Uniprot | |
| K229 | Acetylation | Uniprot | |
| T263 | Phosphorylation | Uniprot | |
| Y461 | Phosphorylation | Uniprot | |
| S474 | Phosphorylation | Uniprot | |
| T479 | Phosphorylation | Uniprot | |
| S492 | Phosphorylation | Uniprot | |
| K539 | Ubiquitination | Uniprot | |
| Y556 | Phosphorylation | Uniprot | |
| Y700 | Phosphorylation | Uniprot | |
| K707 | Acetylation | Uniprot | |
| Y730 | Phosphorylation | Uniprot | |
| T878 | Phosphorylation | Uniprot | |
| K893 | Ubiquitination | Uniprot |
研究背景
Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively.
Mitochondrion.
Expressed in all 16 tissues examined with highest expression in the liver.
Homodimer.
In the N-terminal section; belongs to the AlaDH/PNT family.
In the C-terminal section; belongs to the saccharopine dehydrogenase family.
研究领域
· Metabolism > Amino acid metabolism > Lysine degradation.
· Metabolism > Global and overview maps > Metabolic pathways.
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