| 产品: | SCNN1D 抗体 |
| 货号: | DF3765 |
| 描述: | Rabbit polyclonal antibody to SCNN1D |
| 应用: | WB IHC |
| 反应: | Human |
| 分子量: | 70 KD; 88kD(Calculated). |
| 蛋白号: | P51172 |
| RRID: | AB_2836129 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3765, RRID:AB_2836129.
展开/折叠
Amiloride sensitive sodium channel subunit delta; Amiloride-sensitive sodium channel subunit delta; Delta ENaC; Delta NaCH; Delta-ENaC; Delta-NaCH; DNACH; ENaC Delta; ENaCD; ENaCdelta; Epithelial Na(+) channel subunit delta; MGC149710; MGC149711; Nonvoltage gated sodium channel 1 subunit delta; Nonvoltage-gated sodium channel 1 subunit delta; SCNED; SCNN1D; SCNND_HUMAN; Sodium channel, nonvoltage gated 1, delta;
抗原和靶标
- P51172 SCNND_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRAVLSQKTTPLPRYLWPGHLSGPRRLTWSWCSDHRTPTCRELGSPHPTPCTGPARGWPRRGGGPCGFTSAGHVLCGYPLCLLSGPIQGCGTGLGDSSMAFLSRTSPVAAASFQSRQEARGSILLQSCQLPPQWLSTEAWTGEWKQPHGGALTSRSPGPVAPQRPCHLKGWQHRPTQHNAACKQGQAAAQTPPRPGPPSAPPPPPKEGHQEGLVELPASFRELLTFFCTNATIHGAIRLVCSRGNRLKTTSWGLLSLGALVALCWQLGLLFERHWHRPVLMAVSVHSERKLLPLVTLCDGNPRRPSPVLRHLELLDEFARENIDSLYNVNLSKGRAALSATVPRHEPPFHLDREIRLQRLSHSGSRVRVGFRLCNSTGGDCFYRGYTSGVAAVQDWYHFHYVDILALLPAAWEDSHGSQDGHFVLSCSYDGLDCQARQFRTFHHPTYGSCYTVDGVWTAQRPGITHGVGLVLRVEQQPHLPLLSTLAGIRVMVHGRNHTPFLGHHSFSVRPGTEATISIREDEVHRLGSPYGHCTAGGEGVEVELLHNTSYTRQACLVSCFQQLMVETCSCGYYLHPLPAGAEYCSSARHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAGWTLATLGEQGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWFGASVLSLLELLELLLDASALTLVLGGRRLRRAWFSWPRASPASGASSIKPEASQMPPPAGGTSDDPEPSGPHLPRVMLPGVLAGVSAEESWAGPQPLETLDT
翻译修饰 - P51172 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T229 | Phosphorylation | Uniprot | |
| T232 | Phosphorylation | Uniprot | |
| S242 | Phosphorylation | Uniprot | |
| T296 | Phosphorylation | Uniprot | |
| S339 | Phosphorylation | Uniprot | |
| T341 | Phosphorylation | Uniprot | |
| S363 | Phosphorylation | Uniprot | |
| S506 | Phosphorylation | Uniprot | |
| S508 | Phosphorylation | Uniprot | |
| T513 | Phosphorylation | Uniprot | |
| S735 | Phosphorylation | Uniprot | |
| S790 | Phosphorylation | Uniprot |
研究背景
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Cell membrane>Multi-pass membrane protein.
Heterotrimer containing a delta/SCNN1D, a beta/SCNN1B and a gamma/SCNN1G subunit. The additional delta/SCNN1D subunit exists only in some organisms and can replace the alpha/SCNN1A subunit to form an alternative channel with specific properties.
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1D subfamily.
限制条款
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