| 产品: | ARSG 抗体 |
| 货号: | DF3797 |
| 描述: | Rabbit polyclonal antibody to ARSG |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Rabbit |
| 分子量: | 65 KD; 57kD(Calculated). |
| 蛋白号: | Q96EG1 |
| RRID: | AB_2836154 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3797, RRID:AB_2836154.
展开/折叠
Arsg; ARSG_HUMAN; Arylsulfatase G; Arylsulfatase G precursor; ASG; KIAA1001; PRO1777; UNQ839;
抗原和靶标
Widely expressed, with very low expression in brain, lung, heart and skeletal muscle.
- Q96EG1 ARSG_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGWLFLKVLLAGVSFSGFLYPLVDFCISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTRNFAVTSVGGLPLNETTLAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVDHTVKENTFLWFTGDNGPWAQKCELAGSVGPFTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQPGHRVLFHPNSGAAGEFGALQTVRLERYKAFYITGGARACDGSTGPELQHKFPLIFNLEDDTAEAVPLERGGAEYQAVLPEVRKVLADVLQDIANDNISSADYTQDPSVTPCCNPYQIACRCQAA
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q96EG1 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S69 | Phosphorylation | Uniprot | |
| Y196 | Phosphorylation | Uniprot | |
| Y204 | Phosphorylation | Uniprot | |
| S218 | Phosphorylation | Uniprot | |
| K226 | Ubiquitination | Uniprot | |
| S379 | Phosphorylation | Uniprot | |
| K451 | Ubiquitination | Uniprot |
研究背景
Displays arylsulfatase activity at acidic pH with pseudosubstrates, such as p-nitrocatechol sulfate and also, but with lower activity, p-nitrophenyl sulfate and 4-methylumbelliferyl sulfate.
N-glycosylated.
The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.
Glycosylated.
Lysosome.
Note: Previously observed endoplasmic reticulum localization is most likely due to folding/maturation problems for overexpressed proteins.
Widely expressed, with very low expression in brain, lung, heart and skeletal muscle.
Belongs to the sulfatase family.
研究领域
· Cellular Processes > Transport and catabolism > Lysosome. (View pathway)
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