产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3811, RRID:AB_2836168.
展开/折叠
ABC transporter 10 protein; ABCB10; ABCB10 ATP binding cassette, sub family B (MDR/TAP), member 10; ABCBA_HUMAN; ATP binding cassette sub family B member 10, mitochondrial; ATP binding cassette transporter 10; ATP-binding cassette sub-family B member 10; ATP-binding cassette transporter 10; EST20237; M ABC2; M-ABC2; mitochondrial; Mitochondrial ATP binding cassette 2; Mitochondrial ATP-binding cassette 2; MTABC2;
抗原和靶标
Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon.
- Q9NRK6 ABCBA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRGPPAWPLRLLEPPSPAEPGRLLPVACVWAAASRVPGSLSPFTGLRPARLWGAGPALLWGVGAARRWRSGCRGGGPGASRGVLGLARLLGLWARGPGSCRCGAFAGPGAPRLPRARFPGGPAAAAWAGDEAWRRGPAAPPGDKGRLRPAAAGLPEARKLLGLAYPERRRLAAAVGFLTMSSVISMSAPFFLGKIIDVIYTNPTVDYSDNLTRLCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVGISMMFFVSPNLATFVLSVVPPVSIIAVIYGRYLRKLTKVTQDSLAQATQLAEERIGNVRTVRAFGKEMTEIEKYASKVDHVMQLARKEAFARAGFFGATGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGISIGGLSSFYSELMKGLGAGGRLWELLEREPKLPFNEGVILNEKSFQGALEFKNVHFAYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLDGHDIRQLNPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVAFIRNFPQGFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHRLSTIKNANMVAVLDQGKITEYGKHEELLSKPNGIYRKLMNKQSFISA
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9NRK6 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S80 | Phosphorylation | Uniprot | |
| K159 | Ubiquitination | Uniprot | |
| Y207 | Phosphorylation | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| T212 | Phosphorylation | Uniprot | |
| K265 | Acetylation | Uniprot | |
| K265 | Ubiquitination | Uniprot | |
| T363 | Phosphorylation | Uniprot | |
| K369 | Ubiquitination | Uniprot | |
| K380 | Ubiquitination | Uniprot | |
| K486 | Ubiquitination | Uniprot | |
| K732 | Ubiquitination | Uniprot |
研究背景
May mediate critical mitochondrial transport functions related to heme biosynthesis.
Mitochondrion inner membrane>Multi-pass membrane protein.
Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon.
Homodimer or homooligomer. Interacts with C10orf88/PAAT.
Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.
研究领域
· Environmental Information Processing > Membrane transport > ABC transporters.
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