| 产品: | NCAPG 抗体 |
| 货号: | DF3968 |
| 描述: | Rabbit polyclonal antibody to NCAPG |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Monkey |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit |
| 分子量: | 114 KD; 114kD(Calculated). |
| 蛋白号: | Q9BPX3 |
| RRID: | AB_2836321 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3968, RRID:AB_2836321.
展开/折叠
CAPG; CHCG; Chromosome associated protein G; Chromosome condensation protein G; Condensin complex subunit 3; Condensin subunit CAP G; HCAP G; Melanoma antigen NY MEL 3; NCAPG; Non SMC condensin I complex subunit G; NY MEL 3; XCAP G homolog;
抗原和靶标
- Q9BPX3 CND3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGAERRLLSIKEAFRLAQQPHQNQAKLVVALSRTYRTMDDKTVFHEEFIHYLKYVMVVYKREPAVERVIEFAAKFVTSFHQSDMEDDEEEEDGGLLNYLFTFLLKSHEANSNAVRFRVCLLINKLLGSMPENAQIDDDVFDKINKAMLIRLKDKIPNVRIQAVLALSRLQDPKDDECPVVNAYATLIENDSNPEVRRAVLSCIAPSAKTLPKIVGRTKDVKEAVRKLAYQVLAEKVHMRAMSIAQRVMLLQQGLNDRSDAVKQAMQKHLLQGWLRFSEGNILELLHRLDVENSSEVAVSVLNALFSITPLSELVGLCKNNDGRKLIPVETLTPEIALYWCALCEYLKSKGDEGEEFLEQILPEPVVYADYLLSYIQSIPVVNEEHRGDFSYIGNLMTKEFIGQQLILIIKSLDTSEEGGRKKLLAVLQEILILPTIPISLVSFLVERLLHIIIDDNKRTQIVTEIISEIRAPIVTVGVNNDPADVRKKELKMAEIKVKLIEAKEALENCITLQDFNRASELKEEIKALEDARINLLKETEQLEIKEVHIEKNDAETLQKCLILCYELLKQMSISTGLSATMNGIIESLILPGIISIHPVVRNLAVLCLGCCGLQNQDFARKHFVLLLQVLQIDDVTIKISALKAIFDQLMTFGIEPFKTKKIKTLHCEGTEINSDDEQESKEVEETATAKNVLKLLSDFLDSEVSELRTGAAEGLAKLMFSGLLVSSRILSRLILLWYNPVTEEDVQLRHCLGVFFPVFAYASRTNQECFEEAFLPTLQTLANAPASSPLAEIDITNVAELLVDLTRPSGLNPQAKTSQDYQALTVHDNLAMKICNEILTSPCSPEIRVYTKALSSLELSSHLAKDLLVLLNEILEQVKDRTCLRALEKIKIQLEKGNKEFGDQAEAAQDATLTTTTFQNEDEKNKEVYMTPLRGVKATQASKSTQLKTNRGQRKVTVSARTNRRCQTAEADSESDHEVPEPESEMKMRLPRRAKTAALEKSKLNLAQFLNEDLS
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9BPX3 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Phosphorylation | Uniprot | ||
| K11 | Ubiquitination | Uniprot | |
| K26 | Ubiquitination | Uniprot | |
| S32 | Phosphorylation | Uniprot | |
| K142 | Ubiquitination | Uniprot | |
| K145 | Ubiquitination | Uniprot | |
| K152 | Ubiquitination | Uniprot | |
| K154 | Ubiquitination | Uniprot | |
| S167 | Phosphorylation | Uniprot | |
| S206 | Phosphorylation | Uniprot | |
| K208 | Ubiquitination | Uniprot | |
| K212 | Ubiquitination | Uniprot | |
| K226 | Ubiquitination | Uniprot | |
| K235 | Ubiquitination | Uniprot | |
| R257 | Methylation | Uniprot | |
| K262 | Ubiquitination | Uniprot | |
| K267 | Ubiquitination | Uniprot | |
| T308 | Phosphorylation | P06493 (CDK1) | Uniprot |
| T332 | Phosphorylation | P06493 (CDK1) | Uniprot |
| S390 | Phosphorylation | Uniprot | |
| T397 | Phosphorylation | Uniprot | |
| K410 | Ubiquitination | Uniprot | |
| T463 | Phosphorylation | Uniprot | |
| S467 | Phosphorylation | Uniprot | |
| K491 | Acetylation | Uniprot | |
| K496 | Ubiquitination | Uniprot | |
| K498 | Ubiquitination | Uniprot | |
| K503 | Ubiquitination | Uniprot | |
| K522 | Ubiquitination | Uniprot | |
| K526 | Ubiquitination | Uniprot | |
| K537 | Ubiquitination | Uniprot | |
| K545 | Ubiquitination | Uniprot | |
| K551 | Ubiquitination | Uniprot | |
| T664 | Phosphorylation | Uniprot | |
| T670 | Phosphorylation | Uniprot | |
| S674 | Phosphorylation | Uniprot | |
| S680 | Phosphorylation | Uniprot | |
| T686 | Phosphorylation | Uniprot | |
| K690 | Ubiquitination | Uniprot | |
| S697 | Phosphorylation | Uniprot | |
| S705 | Phosphorylation | Uniprot | |
| K717 | Ubiquitination | Uniprot | |
| T817 | Phosphorylation | Uniprot | |
| S818 | Phosphorylation | Uniprot | |
| Y821 | Phosphorylation | Uniprot | |
| K833 | Ubiquitination | Uniprot | |
| S841 | Phosphorylation | Uniprot | |
| S844 | Phosphorylation | Uniprot | |
| T851 | Phosphorylation | Uniprot | |
| K852 | Ubiquitination | Uniprot | |
| K891 | Ubiquitination | Uniprot | |
| K896 | Ubiquitination | Uniprot | |
| K899 | Ubiquitination | Uniprot | |
| Y929 | Phosphorylation | Uniprot | |
| T931 | Phosphorylation | P06493 (CDK1) | Uniprot |
| R934 | Methylation | Uniprot | |
| K937 | Ubiquitination | Uniprot | |
| K943 | Ubiquitination | Uniprot | |
| S944 | Phosphorylation | Uniprot | |
| T945 | Phosphorylation | Uniprot | |
| S959 | Phosphorylation | Uniprot | |
| T968 | Phosphorylation | Uniprot | |
| S973 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
| S975 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
| S984 | Phosphorylation | Uniprot | |
| T996 | Phosphorylation | Uniprot | |
| S1002 | Phosphorylation | Uniprot | |
| K1003 | Ubiquitination | Uniprot | |
| S1015 | Phosphorylation | Uniprot |
研究背景
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Phosphorylated by CDK1. Its phosphorylation, as well as that of NCAPD2 and NCAPH subunits, activates the condensin complex and is required for chromosome condensation (By similarity).
Nucleus. Cytoplasm. Chromosome.
Note: In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Highly expressed in testis.
Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and NCAPG.
Belongs to the CND3 (condensin subunit 3) family.
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