ATG4D Antibody - #DF3977

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产品: ATG4D 抗体
货号: DF3977
描述: Rabbit polyclonal antibody to ATG4D
应用: WB IHC IF/ICC
文献验证: IF/ICC
反应: Human, Mouse
预测: Pig, Horse, Dog
蛋白号: Q86TL0
RRID: AB_2836337

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
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说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
ATG4D Antibody detects endogenous levels of total ATG4D.
RRID:
AB_2836337
引用格式: Affinity Biosciences Cat# DF3977, RRID:AB_2836337.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

9830134P12Rik; APG4 autophagy 4 homolog D; APG4 D; APG4, S. cerevisiae, homolog of, D; APG4D; ATG4 autophagy related 4 homolog D (S. cerevisiae); Atg4d; ATG4D_HUMAN; Atg4dl; AUT like 4 cysteine endopeptidase; AUT-like 4 cysteine endopeptidase; AUTL4; Autophagin 4; Autophagin-4; autophagy 4, S. cerevisiae, homolog of, D; autophagy related 4D, cysteine peptidase; Autophagy related cysteine endopeptidase 4; Autophagy related protein 4 homolog D; Autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; Cysteine protease ATG4D; Cysteine protease involved in autophagy; MGC31226;

抗原和靶标

免疫原:

A synthesized peptide derived from human ATG4D, corresponding to a region within C-terminal amino acids.

基因/基因ID:
ATG4D(84971)

研究领域

· Cellular Processes > Transport and catabolism > Autophagy - other.   (View pathway)

· Cellular Processes > Transport and catabolism > Autophagy - animal.   (View pathway)

文献引用

1). Targeted inhibition of autophagy in hepatic stellate cells by hydroxychloroquine: An effective therapeutic approach for the treatment of liver fibrosis. Liver international : official journal of the International Association for the Study of the Liver, 2024 (PubMed: 38606676) [IF=6.0]
2). Pathogenic variants of ATG4D in infertile men with non‐obstructive azoospermia identified using whole‐exome sequencing. Clinical Genetics, 2021 (PubMed: 33988247) [IF=2.9]

Application: IF/ICC    Species: Human    Sample: testicular tissue

Figure 3: Immunofluorescence staining of histological sections from the patients with the homozygous pathogenic variant c.374G>T:p.Arg125Leu in ATG4D. (A) Immunofluorescence staining of ATG4D in testicular tissue sections from the control and patients with the ATG4D variants. (B) Immunofluorescence staining of LC3B in the testicular tissue sections. (C) TUNEL assay of testicular tissue sections from the control and patients with the ATG4D variants. The control sample was obtained from a patient with obstructive azoospermia who had normal spermatogenesis. Scale bar = 50 μm.

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