产品: NDUFB10 抗体
货号: DF4207
描述: Rabbit polyclonal antibody to NDUFB10
应用: WB IF/ICC
反应: Human
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Xenopus
分子量: 24 KD; 21kD(Calculated).
蛋白号: O96000
RRID: AB_2836415

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
预测:
Pig(91%), Zebrafish(91%), Bovine(91%), Horse(91%), Sheep(100%), Dog(91%), Xenopus(100%)
克隆:
Polyclonal
特异性:
NDUFB10 Antibody detects endogenous levels of total NDUFB10.
RRID:
AB_2836415
引用格式: Affinity Biosciences Cat# DF4207, RRID:AB_2836415.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

0610011B04Rik; 22kDa; CI PDSW; CI-PDSW; Complex I PDSW; Complex I PDSW subunit; Complex I-PDSW; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 10 22kDa; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10; NADH ubiquinone oxidoreductase PDSW subunit; NADH-ubiquinone oxidoreductase PDSW subunit; NDUBA_HUMAN; NDUFB 10; Ndufb10; PDSW;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
序列:
MPDSWDKDVYPEPPRRTPVQPNPIVYMMKAFDLIVDRPVTLVREFIERQHAKNRYYYYHRQYRRVPDITECKEEDIMCMYEAEMQWKRDYKVDQEIINIMQDRLKACQQREGQNYQQNCIKEVEQFTQVAKAYQDRYQDLGAYSSARKCLAKQRQRMLQERKAAKEAAAATS

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Sheep
100
Xenopus
100
Pig
91
Horse
91
Bovine
91
Dog
91
Zebrafish
91
Chicken
64
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - O96000 作为底物

Site PTM Type Enzyme
S4 Phosphorylation
K7 Ubiquitination
T17 Phosphorylation
Y26 Phosphorylation
Y55 Phosphorylation
Y56 Phosphorylation
Y57 Phosphorylation
K91 Ubiquitination
K105 Ubiquitination
K121 Ubiquitination
K131 Ubiquitination
R136 Methylation
Y137 Phosphorylation
Y143 Phosphorylation
S145 Phosphorylation
K148 Ubiquitination

研究背景

功能:

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

细胞定位:

Mitochondrion inner membrane>Peripheral membrane protein>Matrix side.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Complex I is composed of 45 different subunits.

蛋白家族:

Belongs to the complex I NDUFB10 subunit family.

研究领域

· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).

· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.

· Human Diseases > Neurodegenerative diseases > Parkinson's disease.

· Human Diseases > Neurodegenerative diseases > Huntington's disease.

· Metabolism > Energy metabolism > Oxidative phosphorylation.

· Metabolism > Global and overview maps > Metabolic pathways.

· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling.   (View pathway)

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