产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4093, RRID:AB_2836467.
展开/折叠
Dermal papilla derived protein 2; Dermal papilla-derived protein 2; DERP2; Ghitm; GHITM_HUMAN; Growth hormone inducible transmembrane protein; Growth hormone-inducible transmembrane protein; HSPC282; MICS1; Mitochondrial morphology and cristae structure 1; My021; PTD010; TMBIM5; Transmembrane BAX inhibitor motif containing 5; Transmembrane BAX inhibitor motif containing protein 5; Transmembrane BAX inhibitor motif-containing protein 5;
抗原和靶标
- Q9H3K2 GHITM_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLAARLVCLRTLPSRVFHPAFTKASPVVKNSITKNQWLLTPSREYATKTRIGIRRGRTGQELKEAALEPSMEKIFKIDQMGRWFVAGGAAVGLGALCYYGLGLSNEIGAIEKAVIWPQYVKDRIHSTYMYLAGSIGLTALSAIAISRTPVLMNFMMRGSWVTIGVTFAAMVGAGMLVRSIPYDQSPGPKHLAWLLHSGVMGAVVAPLTILGGPLLIRAAWYTAGIVGGLSTVAMCAPSEKFLNMGAPLGVGLGLVFVSSLGSMFLPPTTVAGATLYSVAMYGGLVLFSMFLLYDTQKVIKRAEVSPMYGVQKYDPINSMLSIYMDTLNIFMRVATMLATGGNRKK
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9H3K2 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K23 | Ubiquitination | Uniprot | |
| K29 | Ubiquitination | Uniprot | |
| K34 | Ubiquitination | Uniprot | |
| T40 | Phosphorylation | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| S70 | Phosphorylation | Uniprot | |
| K73 | Ubiquitination | Uniprot | |
| S185 | Phosphorylation | Uniprot | |
| Y313 | Phosphorylation | Uniprot |
研究背景
Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c.
Mitochondrion inner membrane>Multi-pass membrane protein.
Belongs to the BI1 family.
限制条款
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