| 产品: | GBP3 抗体 |
| 货号: | DF4114 |
| 描述: | Rabbit polyclonal antibody to GBP3 |
| 应用: | WB IF/ICC |
| 反应: | Human |
| 分子量: | 64 KD; 68kD(Calculated). |
| 蛋白号: | Q9H0R5 |
| RRID: | AB_2836479 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4114, RRID:AB_2836479.
展开/折叠
DKFZp686E0974; DKFZp686L15228; FLJ10961; GBP 3; GBP-3; GBP3; GBP3_HUMAN; GTP binding protein 3; GTP-binding protein 3; Guanine nucleotide binding protein 3; Guanine nucleotide-binding protein 3; Guanylate binding protein 3; Guanylate-binding protein 3; guanylate-binding protein 3 delta C; SPG3A;
抗原和靶标
- Q9H0R5 GBP3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAPEIHMTGPMCLIENTNGELVANPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKNKGFSLGSTVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDVKKGDNQNDSWIFTLAVLLSSTLVYNSMGTINQQAMDQLYYVTELTHRIRSKSSPDENENEDSADFVSFFPDFVWTLRDFSLDLEADGQPLTPDEYLEYSLKLTQGTSQKDKNFNLPRLCIRKFFPKKKCFVFDLPIHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIKVNGPRLESLVLTYINAISRGDLPCMENAVLALAQIENSAAVQKAIAHYDQQMGQKVQLPAETLQELLDLHRVSEREATEVYMKNSFKDVDHLFQKKLAAQLDKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYCLFIQKLQDLEKKYYEEPRKGIQAEEILQTYLKSKESVTDAILQTDQILTEKEKEIEVECVKAESAQASAKMVEEMQIKYQQMMEEKEKSYQEHVKQLTEKMERERAQLLEEQEKTLTSKLQEQARVLKERCQGESTQLQNEIQKLQKTLKKKTKRYMSHKLKI
翻译修饰 - Q9H0R5 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S52 | Phosphorylation | Uniprot | |
| S154 | Phosphorylation | Uniprot | |
| S156 | Phosphorylation | Uniprot | |
| S157 | Phosphorylation | Uniprot | |
| K276 | Ubiquitination | Uniprot | |
| Y298 | Phosphorylation | Uniprot | |
| S303 | Phosphorylation | Uniprot | |
| K451 | Ubiquitination | Uniprot | |
| Y462 | Phosphorylation | Uniprot | |
| K518 | Acetylation | Uniprot | |
| K520 | Acetylation | Uniprot | |
| T547 | Phosphorylation | Uniprot | |
| S550 | Phosphorylation | Uniprot | |
| K551 | Ubiquitination | Uniprot |
研究背景
Exhibits antiviral activity against influenza virus.
Cytoplasm. Cytoplasm>Perinuclear region. Golgi apparatus membrane.
Note: Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus.
Heterodimer with other family members, including GBP1, GBP2 and GBP5. Dimerization regulates subcellular location.
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily.
研究领域
· Organismal Systems > Immune system > NOD-like receptor signaling pathway. (View pathway)
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