产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4148, RRID:AB_2836513.
展开/折叠
47 kDa actin binding protein; 47 kDa actin-binding protein; 52 kDa phosphoprotein; F actin binding and cytoskeleton associated protein; Leufactin (leukocyte F-actin binding protein); Leufactin; Leukocyte F actin binding protein; Leukocyte specific protein 1; LSP 1; Lsp1; LSP1_HUMAN; Lymphocyte specific antigen WP34; Lymphocyte specific protein 1; Lymphocyte specific protein pp52; Lymphocyte-specific antigen WP34; Lymphocyte-specific protein 1; OTTHUMP00000014138; OTTHUMP00000014139; OTTHUMP00000014140; OTTHUMP00000069612; OTTHUMP00000069614; OTTHUMP00000069615; OTTHUMP00000069616; pp52; Protein pp52; S37 protein; WP 34; WP34;
抗原和靶标
- P33241 LSP1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAEASSDPGAEEREELLGPTAQWSVEDEEEAVHEQCQHERDRQLQAQDEEGGGHVPERPKQEMLLSLKPSEAPELDEDEGFGDWSQRPEQRQQHEGAQGALDSGEPPQCRSPEGEQEDRPGLHAYEKEDSDEVHLEELSLSKEGPGPEDTVQDNLGAAGAEEEQEEHQKCQQPRTPSPLVLEGTIEQSSPPLSPTTKLIDRTESLNRSIEKSNSVKKSQPDLPISKIDQWLEQYTQAIETAGRTPKLARQASIELPSMAVASTKSRWETGEVQAQSAAKTPSCKDIVAGDMSKKSLWEQKGGSKTSSTIKSTPSGKRYKFVATGHGKYEKVLVEGGPAP
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P33241 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S6 | Phosphorylation | Uniprot | |
| T20 | Phosphorylation | Uniprot | |
| S24 | Phosphorylation | Uniprot | |
| K60 | Ubiquitination | Uniprot | |
| S66 | Phosphorylation | Uniprot | |
| K68 | Ubiquitination | Uniprot | |
| S103 | Phosphorylation | Uniprot | |
| S111 | Phosphorylation | Uniprot | |
| Y125 | Phosphorylation | Uniprot | |
| S130 | Phosphorylation | Uniprot | |
| S139 | Phosphorylation | Uniprot | |
| S141 | Phosphorylation | Uniprot | |
| T175 | Phosphorylation | Uniprot | |
| S177 | Phosphorylation | Uniprot | |
| T184 | Phosphorylation | Uniprot | |
| S188 | Phosphorylation | Uniprot | |
| S189 | Phosphorylation | Uniprot | |
| S193 | Phosphorylation | Uniprot | |
| T195 | Phosphorylation | Uniprot | |
| T196 | Phosphorylation | Uniprot | |
| T202 | Phosphorylation | Uniprot | |
| S204 | Phosphorylation | P49137 (MAPKAPK2) | Uniprot |
| S208 | Phosphorylation | Uniprot | |
| S218 | Phosphorylation | Uniprot | |
| K226 | Ubiquitination | Uniprot | |
| Y234 | Phosphorylation | Uniprot | |
| T235 | Phosphorylation | Uniprot | |
| T244 | Phosphorylation | Uniprot | |
| S252 | Phosphorylation | P49137 (MAPKAPK2) | Uniprot |
| S257 | Phosphorylation | Uniprot | |
| S262 | Phosphorylation | Uniprot | |
| S265 | Phosphorylation | Uniprot | |
| T269 | Phosphorylation | Uniprot | |
| S282 | Phosphorylation | Uniprot | |
| S292 | Phosphorylation | Uniprot | |
| T323 | Phosphorylation | Uniprot | |
| K327 | Acetylation | Uniprot | |
| Y328 | Phosphorylation | Uniprot |
研究背景
May play a role in mediating neutrophil activation and chemotaxis.
Phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. Phosphorylation by PKC induces translocation from membrane to cytoplasm. Phosphorylation by MAPKAPK2 may regulate neutrophil chemotaxis (By similarity).
Cell membrane>Peripheral membrane protein>Cytoplasmic side.
Activated T-lymphocytes.
Binds actin.
研究领域
· Human Diseases > Infectious diseases: Bacterial > Tuberculosis.
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