| 产品: | MAD2L1BP 抗体 |
| 货号: | DF4150 |
| 描述: | Rabbit polyclonal antibody to MAD2L1BP |
| 应用: | WB IF/ICC |
| 反应: | Human |
| 预测: | Pig, Bovine, Horse, Sheep, Dog |
| 分子量: | 31 KD; 31kD(Calculated). |
| 蛋白号: | Q15013 |
| RRID: | AB_2836515 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4150, RRID:AB_2836515.
展开/折叠
Caught by MAD2 protein; CMT2; dJ261G23.1; KIAA0110; MAD2L1 binding protein; MAD2L1 binding protein isoform 2; MAD2L1-binding protein; Mad2l1bp; MD2BP_HUMAN; MGC11282; OTTHUMP00000016496; RP1 261G23.6;
抗原和靶标
- Q15013 MD2BP_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAPEAEVLSSAAVPDLEWYEKSEETHASQIELLETSSTQEPLNASEAFCPRDCMVPVVFPGPVSQEGCCQFTCELLKHIMYQRQQLPLPYEQLKHFYRKPSPQAEEMLKKKPRATTEVSSRKCQQALAELESVLSHLEDFFARTLVPRVLILLGGNALSPKEFYELDLSLLAPYSVDQSLSTAACLRRLFRAIFMADAFSELQAPPLMGTVVMAQGHRNCGEDWFRPKLNYRVPSRGHKLTVTLSCGRPSIRTTAWEDYIWFQAPVTFKGFRE
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q15013 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S23 | Phosphorylation | Uniprot | |
| S29 | Phosphorylation | Uniprot | |
| T36 | Phosphorylation | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| S38 | Phosphorylation | Uniprot | |
| T39 | Phosphorylation | Uniprot | |
| S46 | Phosphorylation | Uniprot | |
| K78 | Ubiquitination | Uniprot | |
| K95 | Ubiquitination | Uniprot | |
| Y98 | Phosphorylation | Uniprot | |
| K100 | Ubiquitination | Uniprot | |
| S102 | Phosphorylation | Uniprot | |
| K110 | Ubiquitination | Uniprot | |
| K229 | Ubiquitination | Uniprot | |
| Y232 | Phosphorylation | Uniprot | |
| S246 | Phosphorylation | Uniprot | |
| S251 | Phosphorylation | Uniprot |
研究背景
May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
Nucleus. Cytoplasm>Cytoskeleton>Spindle.
Note: During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.
Interacts with MAD2L1.
Belongs to the MAD2L1BP family.
限制条款
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