产品: MRPS2 抗体
货号: DF4164
描述: Rabbit polyclonal antibody to MRPS2
应用: WB IHC IF/ICC
反应: Human, Rat
预测: Pig, Bovine, Sheep
分子量: 33 KD; 33kD(Calculated).
蛋白号: Q9Y399
RRID: AB_2836529

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Rat
预测:
Pig(82%), Bovine(82%), Sheep(80%)
克隆:
Polyclonal
特异性:
MRPS2 Antibody detects endogenous levels of total MRPS2.
RRID:
AB_2836529
引用格式: Affinity Biosciences Cat# DF4164, RRID:AB_2836529.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

28S ribosomal protein S2; 28S ribosomal protein S2 mitochondrial; CGI 91; CGI91; Mitochondrial 28S ribosomal protein S2; mitochondrial; Mitochondrial ribosomal protein S2; MRP S2; MRP-S2; MRPS2; OTTHUMP00000022545; OTTHUMP00000022546; RT02_HUMAN; S2mt;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
序列:
MATSSAALPRILGAGARAPSRWLGFLGKATPRPARPSRRTLGSATALMIRESEDSTDFNDKILNEPLKHSDFFNVKELFSVRSLFDARVHLGHKAGCRHRFMEPYIFGSRLDHDIIDLEQTATHLQLALNFTAHMAYRKGIILFISRNRQFSYLIENMARDCGEYAHTRYFRGGMLTNARLLFGPTVRLPDLIIFLHTLNNIFEPHVAVRDAAKMNIPTVGIVDTNCNPCLITYPVPGNDDSPLAVHLYCRLFQTAITRAKEKRQQVEALYRLQGQKEPGDQGPAHPPGADMSHSL

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
82
Bovine
82
Sheep
80
Dog
70
Xenopus
70
Zebrafish
70
Horse
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9Y399 作为底物

Site PTM Type Enzyme
S4 Phosphorylation
S5 Phosphorylation
K28 Ubiquitination
T30 Phosphorylation
S37 Phosphorylation
K61 Ubiquitination
K68 Ubiquitination
S146 Phosphorylation
T255 Phosphorylation
T258 Phosphorylation
Y271 Phosphorylation
K277 Ubiquitination

研究背景

功能:

Required for mitoribosome formation and stability, and mitochondrial translation.

细胞定位:

Mitochondrion.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Component of the mitochondrial small ribosomal subunit (mt-SSU). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins.

蛋白家族:

Belongs to the universal ribosomal protein uS2 family.

研究领域

· Genetic Information Processing > Translation > Ribosome.

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