产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4217, RRID:AB_2836568.
展开/折叠
Cytosolic malic enzyme 1; HUMNDME; Malate dehydrogenase; Malic enzyme 1; Malic enzyme 1, NADP(+) dependent, cytosolic; Malic enzyme 1, soluble; Malic enzyme, cytoplasmic; MAOX_HUMAN; ME1; MES; NADP dependent malic enzyme; NADP ME; NADP-dependent malic enzyme; NADP-ME; Pyruvic malic carboxylase;
抗原和靶标
Expressed in all tissues tested including liver, placenta and white adipose tissue.
- P48163 MAOX_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEPEAPRRRHTHQRGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQGAGEAALGIAHLIVMALEKEGLPKEKAIKKIWLVDSKGLIVKGRASLTQEKEKFAHEHEEMKNLEAIVQEIKPTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKITKGRAIFASGSPFDPVTLPNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLTTAEVIAQQVSDKHLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFVRSQMYSTDYDQILPDCYSWPEEVQKIQTKVDQ
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P48163 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| K26 | Ubiquitination | Uniprot | |
| K60 | Acetylation | Uniprot | |
| K60 | Ubiquitination | Uniprot | |
| S67 | Phosphorylation | Uniprot | |
| K84 | Acetylation | Uniprot | |
| K84 | Ubiquitination | Uniprot | |
| S92 | Phosphorylation | Uniprot | |
| Y113 | Phosphorylation | Uniprot | |
| T151 | Phosphorylation | Uniprot | |
| Y208 | Phosphorylation | Uniprot | |
| S336 | Phosphorylation | Uniprot | |
| K337 | Ubiquitination | Uniprot | |
| K351 | Ubiquitination | Uniprot | |
| K353 | Ubiquitination | Uniprot | |
| K412 | Ubiquitination | Uniprot | |
| K422 | Ubiquitination | Uniprot | |
| T474 | Phosphorylation | Uniprot | |
| K492 | Ubiquitination | Uniprot | |
| S510 | Phosphorylation | Uniprot | |
| K512 | Ubiquitination | Uniprot | |
| K516 | Ubiquitination | Uniprot | |
| K519 | Ubiquitination | Uniprot | |
| K525 | Ubiquitination | Uniprot | |
| K536 | Ubiquitination | Uniprot | |
| K569 | Sumoylation | Uniprot | |
| K569 | Ubiquitination | Uniprot |
研究背景
Cytoplasm.
Expressed in all tissues tested including liver, placenta and white adipose tissue.
Homotetramer.
Belongs to the malic enzymes family.
研究领域
· Metabolism > Carbohydrate metabolism > Pyruvate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > Carbon metabolism.
· Organismal Systems > Endocrine system > PPAR signaling pathway.
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