产品: NCR1 抗体
货号: DF4220
描述: Rabbit polyclonal antibody to NCR1
应用: WB IF/ICC
反应: Human
分子量: 40 KD; 34kD(Calculated).
蛋白号: O76036
RRID: AB_2836571

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 50ul RMB¥ 1250 现货
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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
NCR1 Antibody detects endogenous levels of total NCR1.
RRID:
AB_2836571
引用格式: Affinity Biosciences Cat# DF4220, RRID:AB_2836571.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Activating NK receptor NK p46; CD335; FLJ99094; hNKp46; Ly94; Lymphocyte antigen 94; Lymphocyte antigen 94 homolog (activating NK receptor; NK p46); Lymphocyte antigen 94 homolog; Natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; NCR1; NCT1; NCTR1_HUMAN; NK cell activating receptor; NK cell-activating receptor; NK-p46; NKp46;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
O76036 NCTR1_HUMAN:

Selectively expressed by both resting and activated NK cells.

序列:
MSSTLPALLCVGLCLSQRISAQQQTLPKPFIWAEPHFMVPKEKQVTICCQGNYGAVEYQLHFEGSLFAVDRPKPPERINKVKFYIPDMNSRMAGQYSCIYRVGELWSEPSNLLDLVVTEMYDTPTLSVHPGPEVISGEKVTFYCRLDTATSMFLLLKEGRSSHVQRGYGKVQAEFPLGPVTTAHRGTYRCFGSYNNHAWSFPSEPVKLLVTGDIENTSLAPEDPTFPADTWGTYLLTTETGLQKDHALWDHTAQNLLRMGLAFLVLVALVWFLVEDWLSRKRTRERASRASTWEGRRRLNTQTL

翻译修饰 - O76036 作为底物

Site PTM Type Enzyme
Y84 Phosphorylation
S90 Phosphorylation
T292 Phosphorylation

研究背景

功能:

Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

翻译修饰:

N-glycosylated.

O-glycosylated.

细胞定位:

Cell membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Selectively expressed by both resting and activated NK cells.

亚基结构:

Interacts with CD247 and FCER1G.

蛋白家族:

Belongs to the natural cytotoxicity receptor (NCR) family.

研究领域

· Organismal Systems > Immune system > Natural killer cell mediated cytotoxicity.   (View pathway)

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