| 产品: | NUP107 抗体 |
| 货号: | DF4250 |
| 描述: | Rabbit polyclonal antibody to NUP107 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 106 KD; 106kD(Calculated). |
| 蛋白号: | P57740 |
| RRID: | AB_2836601 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4250, RRID:AB_2836601.
展开/折叠
107 kDa nucleoporin; NU107_HUMAN; Nuclear pore complex protein Nup107; Nucleoporin 107kDa; Nucleoporin Nup107; NUP107; NUP84; NUP84, yeast, homolog of; OTTHUMP00000240604; OTTHUMP00000240606;
抗原和靶标
- P57740 NU107_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFRQPFTPTSRSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEEYENICGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVFAVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPREYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P57740 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| S4 | Phosphorylation | Uniprot | |
| S10 | Phosphorylation | P24941 (CDK2) | Uniprot |
| S11 | Phosphorylation | P24941 (CDK2) | Uniprot |
| T22 | Phosphorylation | Uniprot | |
| K25 | Methylation | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| T45 | Phosphorylation | Uniprot | |
| T46 | Phosphorylation | Uniprot | |
| T55 | Phosphorylation | Uniprot | |
| S57 | Phosphorylation | Uniprot | |
| S58 | Phosphorylation | Uniprot | |
| R60 | Methylation | Uniprot | |
| T64 | Phosphorylation | Uniprot | |
| T66 | Phosphorylation | Uniprot | |
| S67 | Phosphorylation | Uniprot | |
| R68 | Methylation | Uniprot | |
| S69 | Phosphorylation | Uniprot | |
| S77 | Phosphorylation | Uniprot | |
| C78 | S-Nitrosylation | Uniprot | |
| T82 | Phosphorylation | Uniprot | |
| K85 | Ubiquitination | Uniprot | |
| S86 | Phosphorylation | Uniprot | |
| S119 | Phosphorylation | Uniprot | |
| S129 | Phosphorylation | Uniprot | |
| S153 | Phosphorylation | Uniprot | |
| S156 | Phosphorylation | Uniprot | |
| T196 | Phosphorylation | Uniprot | |
| K201 | Ubiquitination | Uniprot | |
| S232 | Phosphorylation | Uniprot | |
| T251 | Phosphorylation | Uniprot | |
| Y296 | Phosphorylation | Uniprot | |
| K305 | Methylation | Uniprot | |
| K305 | Ubiquitination | Uniprot | |
| S315 | Phosphorylation | Uniprot | |
| T321 | Phosphorylation | Uniprot | |
| K332 | Ubiquitination | Uniprot | |
| K348 | Ubiquitination | Uniprot | |
| K382 | Ubiquitination | Uniprot | |
| K408 | Ubiquitination | Uniprot | |
| K491 | Ubiquitination | Uniprot | |
| K501 | Ubiquitination | Uniprot | |
| K502 | Ubiquitination | Uniprot | |
| Y512 | Phosphorylation | Uniprot | |
| S569 | Phosphorylation | Uniprot | |
| K626 | Ubiquitination | Uniprot | |
| K637 | Ubiquitination | Uniprot | |
| K646 | Ubiquitination | Uniprot | |
| K690 | Ubiquitination | Uniprot | |
| S702 | Phosphorylation | Uniprot | |
| K709 | Acetylation | Uniprot | |
| K709 | Ubiquitination | Uniprot | |
| K714 | Acetylation | Uniprot | |
| K773 | Ubiquitination | Uniprot | |
| K785 | Ubiquitination | Uniprot | |
| K803 | Ubiquitination | Uniprot | |
| K814 | Ubiquitination | Uniprot | |
| K816 | Ubiquitination | Uniprot | |
| K837 | Ubiquitination | Uniprot |
研究背景
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis.
Nucleus membrane. Nucleus>Nuclear pore complex. Chromosome>Centromere>Kinetochore.
Note: Located on both the cytoplasmic and nuclear sides of the NPC core structure (PubMed:11564755). During mitosis, localizes to the kinetochores (PubMed:11564755). Dissociates from the dissasembled NPC structure late during prophase of mitosis (PubMed:11564755).
Ubiquitously expressed in fetal and adult tissues.
Part of the nuclear pore complex (NPC). Forms part of the Nup160 subcomplex in the nuclear pore which is composed of NUP160, NUP133, NUP107 and Nup96; this complex plays a role in RNA export and in tethering Nup98 and NUP153 to the nucleus. Does not interact with TPR. Interacts with ZNF106 (By similarity).
Belongs to the nucleoporin Nup84/Nup107 family.
研究领域
· Genetic Information Processing > Translation > RNA transport.
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