NUP93 Antibody - #DF4252

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产品: NUP93 抗体
货号: DF4252
描述: Rabbit polyclonal antibody to NUP93
应用: WB
反应: Human, Mouse, Rat
预测: Dog
分子量: 93 KD; 93kD(Calculated).
蛋白号: Q8N1F7
RRID: AB_2836603

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
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实验方案
WB Handbook
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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Dog(89%)
克隆:
Polyclonal
特异性:
NUP93 Antibody detects endogenous levels of total NUP93.
RRID:
AB_2836603
引用格式: Affinity Biosciences Cat# DF4252, RRID:AB_2836603.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

2410008G02Rik; 93 kDa nucleoporin; CBP-interacting protein 4; Dead eye protein; Dye; KIAA0095; MGC21106; NIC96; NIC96, S. cerevisiae, homolog of; Nuclear pore complex protein Nup93; Nucleoporin 93; Nucleoporin 93kDa; Nucleoporin Nup93;

抗原和靶标

免疫原:
Uniprot:

Q8N1F7(NUP93_HUMAN) >>Visit HPA database.

基因/基因ID:
NUP93(9688)
序列:
MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETADVKASVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYISDVGPPGRSSLDNIEMAYARQIYIYNEKIVNGHLQPNLVDLCASVAELDDKSISDMWTMVKQMTDVLLTPATDALKNRSSVEVRMEFVRQALAYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAPLPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVNRAQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDVTDNQSEVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAVAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCLRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGENMFLRCVSELVIESREFDMILGKLENDGSRKPGVIDKFTSDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNKERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIERLKLVPLNQESVEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSSSRPQRVIEDRDSQLRSQARTLITFAGMIPYRTSGDTNARLVQMEVLMN

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Dog
89
Pig
78
Bovine
78
Sheep
78
Rabbit
78
Horse
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q8N1F7 作为底物

Site PTM Type Enzyme
T3 Phosphorylation
S45 Phosphorylation
T47 Phosphorylation
T49 Phosphorylation
T51 Phosphorylation
S52 Phosphorylation
T55 Phosphorylation
K59 Ubiquitination
S66 Phosphorylation
R67 Methylation
S72 Phosphorylation
S75 Phosphorylation
S80 Phosphorylation
K94 Ubiquitination
K103 Acetylation
K103 Sumoylation
K103 Ubiquitination
K106 Acetylation
K106 Ubiquitination
S112 Phosphorylation
S117 Phosphorylation
K119 Ubiquitination
R120 Methylation
Y128 Phosphorylation
K141 Ubiquitination
T159 Phosphorylation
S162 Phosphorylation
S165 Phosphorylation
Y166 Phosphorylation
S168 Phosphorylation
Y185 Phosphorylation
Y190 Phosphorylation
T231 Phosphorylation
T236 Phosphorylation
K243 Ubiquitination
K349 Ubiquitination
T350 Phosphorylation
K359 Ubiquitination
S364 Phosphorylation
T367 Phosphorylation
K370 Ubiquitination
K387 Ubiquitination
Y391 Phosphorylation
K409 Ubiquitination
Y413 Phosphorylation
K417 Ubiquitination
S430 Phosphorylation
R434 Methylation
S438 Phosphorylation
T536 Phosphorylation
Y550 Phosphorylation
K558 Ubiquitination
S560 Phosphorylation
S571 Phosphorylation
K586 Ubiquitination
K594 Ubiquitination
K600 Ubiquitination
S603 Phosphorylation
K606 Sumoylation
K606 Ubiquitination
K611 Ubiquitination
S614 Phosphorylation
K619 Acetylation
K619 Ubiquitination
K627 Ubiquitination
K633 Ubiquitination
K637 Acetylation
K637 Ubiquitination
K644 Ubiquitination
S647 Phosphorylation
S654 Phosphorylation
S658 Phosphorylation
K660 Ubiquitination
K664 Ubiquitination
K718 Ubiquitination
S726 Phosphorylation
T758 Phosphorylation
K764 Ubiquitination
T766 Phosphorylation
S767 Phosphorylation
S770 Phosphorylation
S771 Phosphorylation
S772 Phosphorylation

研究背景

功能:

Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.

细胞定位:

Nucleus membrane>Peripheral membrane protein. Nucleus>Nuclear pore complex. Nucleus envelope.
Note: Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Part of the nuclear pore complex (NPC). Component of the p62 complex, a complex composed of NUP62 and NUP54. Forms a complex with NUP35, NUP155, NUP205 and lamin B; the interaction with NUP35 is direct. Does not interact with TPR. Interacts with SMAD4 and IPO7; translocates SMAD4 to the nucleus through the NPC upon BMP7 stimulation resulting in activation of SMAD4 signaling.

蛋白家族:

Belongs to the nucleoporin interacting component (NIC) family.

研究领域

· Genetic Information Processing > Translation > RNA transport.

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