| 产品: | NXF3 抗体 |
| 货号: | DF4258 |
| 描述: | Rabbit polyclonal antibody to NXF3 |
| 应用: | WB IF/ICC |
| 反应: | Human |
| 预测: | Dog |
| 分子量: | 60 KD; 60kD(Calculated). |
| 蛋白号: | Q9H4D5 |
| RRID: | AB_2836609 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4258, RRID:AB_2836609.
展开/折叠
Nuclear RNA export factor 3; NXF3; NXF3_HUMAN; OTTHUMP00000023726; OTTHUMP00000023727; TAP like protein 3; TAP-like protein 3; TAPL 3; TAPL-3; TAPL3;
抗原和靶标
- Q9H4D5 NXF3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLPSGHTTGHTDQVVQRRARCWDIYQRRFSSRSEPVNPGMHSSSHQQQDGDAAMHGAHMDSPVRYTPYTISPYNRKGSFRKQDQTHVNMEREQKPPERRMEGNMPDGTLGSWFKITVPFGIKYNEKWLLNLIQNECSVPFVPVEFHYENMHASFFVENASIAYALKNVSGKIWDEDNEKISIFVNPAGIPHFVHRELKSEKVEQIKLAMNQQCDVSQEALDIQRLPFYPDMVNRDTKMASNPRKCMAASLDVHEENIPTVMSAGEMDKWKGIEPGEKCADRSPVCTTFSDTSSNINSILELFPKLLCLDGQQSPRATLCGTEAHKRLPTCKGSFFGSEMLKNLVLQFLQQYYLIYDSGDRQGLLSAYHDEACFSLSIPFNPEDSAPSSFCKFFKDSRNIKILKDPYLRGELLKHTKLDIVDSLSALPKTQHDLSSFLVDMWYQTEWMLCFSVNGVFKEVEGQSQGSVLAFTRTFIATPGSSSSLCIVNDKLFVRDTSHQGTQSALFTLVPTAFSSSVPAFSQEQQKMLPS
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9H4D5 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y124 | Phosphorylation | Uniprot | |
| Y407 | Phosphorylation | Uniprot |
研究背景
May function as a tissue-specific nuclear mRNA export factor.
Nucleus. Cytoplasm.
Note: Shuttles between the nucleus and the cytoplasm.
Expressed at high level in testis and at low level in a small number of tissues.
Interacts with NXT1, NXT2, E1B-AP5 and CRM1 nuclear export factor.
Lacks C-terminal domain that mediates direct interactions with nucleoporins.
Contains a novel CRM1-dependent nuclear export signal that compensates in cis for the loss of the nuclear pore targeting domain.
The RNA-binding domain is a non-canonical RNP-type domain.
Belongs to the NXF family.
研究领域
· Genetic Information Processing > Translation > Ribosome biogenesis in eukaryotes.
· Genetic Information Processing > Translation > RNA transport.
· Genetic Information Processing > Translation > mRNA surveillance pathway.
· Human Diseases > Infectious diseases: Viral > Influenza A.
· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.
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