产品: | NFYC 抗体 |
货号: | DF4259 |
描述: | Rabbit polyclonal antibody to NFYC |
应用: | WB IF/ICC |
反应: | Human, Mouse, Rat |
预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
分子量: | 50 KD; 50kD(Calculated). |
蛋白号: | Q13952 |
RRID: | AB_2836610 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4259, RRID:AB_2836610.
展开/折叠
CAAT box DNA binding protein subunit C; CAAT box DNA-binding protein subunit C; CBF C; CBFC; CCAAT binding factor subunit C; CCAAT transcription binding factor subunit gamma; DKFZp667G242; FLJ45775; H1TF2A; HAP5; histone H1 transcription factor large subunit 2A; HSM; NF-YC; NFYC; NFYC_HUMAN; Nuclear transcription factor Y gamma; Nuclear transcription factor Y subunit C; Nuclear transcription factor Y subunit gamma; OTTHUMP00000009207; OTTHUMP00000009208; OTTHUMP00000009209; OTTHUMP00000009210; OTTHUMP00000009211; OTTHUMP00000009212; OTTHUMP00000009213; OTTHUMP00000009215; OTTHUMP00000009217; OTTHUMP00000231028; Transactivator HSM 1/2; transactivator HSM-1; Transactivator HSM-1/2;
抗原和靶标
- Q13952 NFYC_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRDELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQGQRNASQGKPRRCLKETLQITQTEVQQGQQQFSQFTDGQRNSVQQARVSELTGEAEPREVKATGNSTPCTSSLPTTHPPSHRAGASCVCCSQPQQSSTSPPPSDALQWVVVEVSGTPNQLETHRELHAPLPGMTSLSPLHPSQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q13952 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
K36 | Ubiquitination | Uniprot | |
K53 | Ubiquitination | Uniprot | |
K59 | Ubiquitination | Uniprot | |
K92 | Ubiquitination | Uniprot | |
K124 | Ubiquitination | Uniprot | |
K127 | Ubiquitination | Uniprot | |
K285 | Ubiquitination | Uniprot | |
T343 | Phosphorylation | Uniprot |
研究背景
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
Nucleus.
Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding.
Belongs to the NFYC/HAP5 subunit family.
研究领域
· Human Diseases > Infectious diseases: Bacterial > Tuberculosis.
· Organismal Systems > Immune system > Antigen processing and presentation. (View pathway)
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