| 产品: | PIGX 抗体 |
| 货号: | DF4293 |
| 描述: | Rabbit polyclonal antibody to PIGX |
| 应用: | WB IF/ICC |
| 反应: | Human |
| 预测: | Pig, Bovine, Horse, Dog |
| 分子量: | 26 KD; 29kD(Calculated). |
| 蛋白号: | Q8TBF5 |
| RRID: | AB_2836644 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4293, RRID:AB_2836644.
展开/折叠
GPI mannosyltransferase subunit; Phosphatidylinositol glycan class X; Phosphatidylinositol-glycan biosynthesis class X protein; PIG-X; Pigx; PIGX_HUMAN;
抗原和靶标
- Q8TBF5 PIGX_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAARVAAVRAAAWLLLGAATGLTRGPAAAFTAARSDAGIRAMCSEIILRQEVLKDGFHRDLLIKVKFGESIEDLHTCRLLIKQDIPAGLYVDPYELASLRERNITEAVMVSENFDIEAPNYLSKESEVLIYARRDSQCIDCFQAFLPVHCRYHRPHSEDGEASIVVNNPDLLMFCDQEFPILKCWAHSEVAAPCALENEDICQWNKMKYKSVYKNVILQVPVGLTVHTSLVCSVTLLITILCSTLILVAVFKYGHFSL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q8TBF5 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T31 | O-Glycosylation | Uniprot | |
| K54 | Ubiquitination | Uniprot | |
| K66 | Ubiquitination | Uniprot | |
| K82 | Ubiquitination | Uniprot |
研究背景
Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM (By similarity).
N-glycosylated.
Endoplasmic reticulum membrane>Single-pass type I membrane protein.
Interacts with PIGM.
Belongs to the PIGX family.
研究领域
· Metabolism > Glycan biosynthesis and metabolism > Glycosylphosphatidylinositol (GPI)-anchor biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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