产品: PRPF38A 抗体
货号: DF4329
描述: Rabbit polyclonal antibody to PRPF38A
应用: WB IF/ICC
反应: Human, Mouse
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 40 KD; 37kD(Calculated).
蛋白号: Q8NAV1
RRID: AB_2836697

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 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(80%)
克隆:
Polyclonal
特异性:
PRPF38A Antibody detects endogenous levels of total PRPF38A.
RRID:
AB_2836697
引用格式: Affinity Biosciences Cat# DF4329, RRID:AB_2836697.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

2410002M20Rik; FLJ14936; MGC3320; OTTMUSP00000008592; PR38A_HUMAN; Pre mRNA splicing factor 38A; Pre-mRNA-splicing factor 38A; Prp38; PRP38 pre mRNA processing factor 38 (yeast) domain containing A; PRP38 pre mRNA processing factor 38 domain containing A; prpf38a; RGD1311129; RP23-406B13.4; RP5 965L7.1;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
序列:
MANRTVKDAHSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELRFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRMLGALYMRLTGTAIDCYKYLEPLYNDYRKIKSQNRNGEFELMHVDEFIDELLHSERVCDIILPRLQKRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGNE

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
80
Zebrafish
60
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q8NAV1 作为底物

Site PTM Type Enzyme
K7 Methylation
K7 Ubiquitination
S11 Phosphorylation
T15 Phosphorylation
K23 Acetylation
K23 Ubiquitination
K66 Ubiquitination
K92 Sumoylation
K97 Acetylation
K97 Ubiquitination
K118 Ubiquitination
K129 Ubiquitination
Y169 Phosphorylation
S182 Phosphorylation
S193 Phosphorylation
S194 Phosphorylation
S209 Phosphorylation
S216 Phosphorylation
S226 Phosphorylation
T228 Phosphorylation
S250 Phosphorylation
S252 Phosphorylation
S260 Phosphorylation
S262 Phosphorylation
S268 Phosphorylation
S270 Phosphorylation
S277 Phosphorylation
S279 Phosphorylation
S281 Phosphorylation
S292 Phosphorylation
S294 Phosphorylation
S296 Phosphorylation

研究背景

功能:

Involved in pre-mRNA splicing as a component of the spliceosome.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Component of the spliceosome B complex (Probable). Interacts (via N-terminal interaction domain) with ZMAT2 AND MFAP1 (Probable).

蛋白家族:

Belongs to the PRP38 family.

研究领域

· Genetic Information Processing > Transcription > Spliceosome.

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