| 产品: | FNTB 抗体 |
| 货号: | DF4339 |
| 描述: | Rabbit polyclonal antibody to FNTB |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Rabbit, Dog |
| 分子量: | 49 KD; 49kD(Calculated). |
| 蛋白号: | P49356 |
| RRID: | AB_2836707 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4339, RRID:AB_2836707.
展开/折叠
CAAX farnesyltransferase subunit beta; EC 2.5.1.58; EC=2.5.1.58; Farnesyltransferase; farnesyltransferase CAAX box beta1; farnesyltransferase, CAAX box, beta; FNTB; FNTB_HUMAN; FPTB; FTase beta; FTase-beta; MGC105303; Protein farnesyltransferase subunit beta; RAS proteins prenyltransferase beta; Ras proteins prenyltransferase subunit beta;
抗原和靶标
- P49356 FNTB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASPSSFTYYCPPSSSPVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATTYFLQKPVPGFEELKDETSAEPATD
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P49356 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S3 | Phosphorylation | Uniprot | |
| S16 | Phosphorylation | Uniprot | |
| S39 | Phosphorylation | Uniprot | |
| T42 | Phosphorylation | Uniprot | |
| K50 | Ubiquitination | Uniprot | |
| K54 | Ubiquitination | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| Y300 | Phosphorylation | Uniprot | |
| K418 | Ubiquitination | Uniprot | |
| T436 | Phosphorylation | Uniprot |
研究背景
Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
Heterodimer of FNTA and FNTB.
Belongs to the protein prenyltransferase subunit beta family.
研究领域
· Metabolism > Metabolism of terpenoids and polyketides > Terpenoid backbone biosynthesis.
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