产品: PPP1R16A 抗体
货号: DF4344
描述: Rabbit polyclonal antibody to PPP1R16A
应用: WB
反应: Human, Rat
分子量: 60~70kD; 58kD(Calculated).
蛋白号: Q96I34
RRID: AB_2836712

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Rat
克隆:
Polyclonal
特异性:
PPP1R16A Antibody detects endogenous levels of total PPP1R16A.
RRID:
AB_2836712
引用格式: Affinity Biosciences Cat# DF4344, RRID:AB_2836712.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

2900084E10Rik; Likley ortholog of mouse myosin phosphatase targeting subunit 3; MGC14333; Myosin phosphatase target subunit 3; Myosin phosphatase targeting subunit 3; Myosin phosphatase-targeting subunit 3; MYPT3; PP16A_HUMAN; PPP1R16A; Protein phosphatase 1 regulatory subunit 16A; Protein phosphatase 1, regulatory (inhibitor) subunit 16A; R75527;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
序列:
MAEHLELLAEMPMVGRMSTQERLKHAQKRRAQQVKMWAQAEKEAQGKKGPGERPRKEAASQGLLKQVLFPPSVVLLEAAARNDLEEVRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLAVNTDGNMPYDLCDDEQTLDCLETAMADRGITQDSIEAARAVPELRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRASLSAKDQDGWEPLHAAAYWGQVPLVELLVAHGADLNAKSLMDETPLDVCGDEEVRAKLLELKHKHDALLRAQSRQRSLLRRRTSSAGSRGKVVRRVSLTQRTDLYRKQHAQEAIVWQQPPPTSPEPPEDNDDRQTGAELRPPPPEEDNPEVVRPHNGRVGGSPVRHLYSKRLDRSVSYQLSPLDSTTPHTLVHDKAHHTLADLKRQRAAAKLQRPPPEGPESPETAEPGLPGDTVTPQPDCGFRAGGDPPLLKLTAPAVEAPVERRPCCLLM

翻译修饰 - Q96I34 作为底物

Site PTM Type Enzyme
S18 Phosphorylation
S60 Phosphorylation
S199 Phosphorylation
S353 Phosphorylation
S418 Phosphorylation
S433 Phosphorylation
Y434 Phosphorylation
S437 Phosphorylation
K451 Acetylation
K460 Acetylation
K460 Ubiquitination
S478 Phosphorylation
T511 Phosphorylation

研究背景

功能:

Inhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates.

细胞定位:

Cell membrane>Lipid-anchor.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Binds PP1.

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