| 产品: | RCL1 抗体 |
| 货号: | DF4444 |
| 描述: | Rabbit polyclonal antibody to RCL1 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 41 KD; 41kD(Calculated). |
| 蛋白号: | Q9Y2P8 |
| RRID: | AB_2836799 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4444, RRID:AB_2836799.
展开/折叠
RCL1; RNA 3' terminal phosphate cyclase like protein; RNA cyclase homolog; RNA terminal phosphate cyclase like 1; RNAC; RPC2; RPCL1; RTC2;
抗原和靶标
- Q9Y2P8 RCL1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATQAHSLSYAGCNFLRQRLVLSTLSGRPVKIRKIRARDDNPGLRDFEASFIRLLDKITNGSRIEINQTGTTLYYQPGLLYGGSVEHDCSVLRGIGYYLESLLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKQFGIDGESFELKIVRRGMPPGGGGEVVFSCPVRKVLKPIQLTDPGKIKRIRGMAYSVRVSPQMANRIVDSARSILNKFIPDIYIYTDHMKGVNSGKSPGFGLSLVAETTSGTFLSAELASNPQGQGAAVLPEDLGRNCARLLLEEIYRGGCVDSTNQSLALLLMTLGQQDVSKVLLGPLSPYTIEFLRHLKSFFQIMFKIETKPCGEELKGGDKVLMTCVGIGFSNLSKTLK
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9Y2P8 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S26 | Phosphorylation | Uniprot | |
| T59 | Phosphorylation | Uniprot | |
| S62 | Phosphorylation | Uniprot | |
| T71 | Phosphorylation | Uniprot | |
| Y74 | Phosphorylation | Uniprot | |
| Y75 | Phosphorylation | Uniprot | |
| Y81 | Phosphorylation | Uniprot | |
| K114 | Ubiquitination | Uniprot | |
| R118 | Methylation | Uniprot | |
| K133 | Ubiquitination | Uniprot | |
| K141 | Ubiquitination | Uniprot | |
| S170 | Phosphorylation | Uniprot | |
| K175 | Ubiquitination | Uniprot | |
| K178 | Ubiquitination | Uniprot | |
| T183 | Phosphorylation | Uniprot | |
| K187 | Ubiquitination | Uniprot | |
| R207 | Methylation | Uniprot | |
| Y224 | Phosphorylation | Uniprot | |
| S321 | Phosphorylation | Uniprot | |
| S333 | Phosphorylation | Uniprot | |
| K351 | Ubiquitination | Uniprot | |
| T359 | Phosphorylation | Uniprot | |
| S366 | Phosphorylation | Uniprot | |
| S369 | Phosphorylation | Uniprot |
研究背景
Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity).
Nucleus>Nucleolus.
Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
研究领域
· Genetic Information Processing > Translation > Ribosome biogenesis in eukaryotes.
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