ATP1B3 Antibody - #DF4528

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产品: ATP1B3 抗体
货号: DF4528
描述: Rabbit polyclonal antibody to ATP1B3
应用: WB IF/ICC
反应: Human, Rat
预测: Pig, Bovine, Sheep, Rabbit, Dog
分子量: 31 KD; 32kD(Calculated).
蛋白号: P54709
RRID: AB_2836879

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Rat
预测:
Pig(91%), Bovine(%), Sheep(%), Rabbit(%), Dog(%)
克隆:
Polyclonal
特异性:
ATP1B3 Antibody detects endogenous levels of total ATP1B3.
RRID:
AB_2836879
引用格式: Affinity Biosciences Cat# DF4528, RRID:AB_2836879.
偶联:
Unconjugated. 130
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

AT1B3_HUMAN; atp1b3; ATPase Na+/K+ transporting beta 3 polypeptide; ATPB 3; ATPB-3; ATPB3; CD 298; CD298; CD298 antigen; FLJ29027; Na K ATPase beta 3 polypeptide; Na+/K+ ATPase beta 3 subunit; NKAB3S; Sodium potassium ATPase subunit beta 3 (non catalytic); Sodium pump subunit beta 3; Sodium/potassium dependent ATPase beta 3 subunit; Sodium/potassium dependent ATPase subunit beta 3; Sodium/potassium transporting ATPase beta 3 chain; Sodium/potassium transporting ATPase subunit beta 3; Sodium/potassium-dependent ATPase subunit beta-3; Sodium/potassium-transporting ATPase subunit beta-3;

抗原和靶标

免疫原:
Uniprot:

P54709(AT1B3_HUMAN) >>Visit HPA database.

基因/基因ID:
ATP1B3(483)
序列:
MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Rabbit
92
Pig
91
Bovine
91
Sheep
91
Dog
91
Horse
64
Chicken
45
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P54709 作为底物

Site PTM Type Enzyme
K7 Ubiquitination
S8 Phosphorylation
S12 Phosphorylation
K17 Ubiquitination
K86 Ubiquitination
T101 Phosphorylation
S102 Phosphorylation
Y103 Phosphorylation
Y106 Phosphorylation
K111 Acetylation
K111 Ubiquitination
K112 Acetylation
K112 Ubiquitination
K115 Ubiquitination
K123 Ubiquitination
K137 Ubiquitination
K182 Ubiquitination
K194 Ubiquitination
K213 Ubiquitination
K220 Ubiquitination
K221 Ubiquitination
N240 N-Glycosylation
K251 Ubiquitination
K259 Ubiquitination
K266 Ubiquitination
K274 Ubiquitination

研究背景

功能:

This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known.

细胞定位:

Cell membrane>Single-pass type II membrane protein. Melanosome.
Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

The sodium/potassium-transporting ATPase is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit.

蛋白家族:

The C-terminal lobe folds into an immunoglobulin-like domain and may mediate cell adhesion properties.

Belongs to the X(+)/potassium ATPases subunit beta family.

研究领域

· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > cAMP signaling pathway.   (View pathway)

· Organismal Systems > Circulatory system > Cardiac muscle contraction.   (View pathway)

· Organismal Systems > Circulatory system > Adrenergic signaling in cardiomyocytes.   (View pathway)

· Organismal Systems > Endocrine system > Insulin secretion.   (View pathway)

· Organismal Systems > Endocrine system > Thyroid hormone synthesis.

· Organismal Systems > Endocrine system > Thyroid hormone signaling pathway.   (View pathway)

· Organismal Systems > Endocrine system > Aldosterone synthesis and secretion.

· Organismal Systems > Excretory system > Aldosterone-regulated sodium reabsorption.

· Organismal Systems > Excretory system > Endocrine and other factor-regulated calcium reabsorption.

· Organismal Systems > Excretory system > Proximal tubule bicarbonate reclamation.

· Organismal Systems > Digestive system > Salivary secretion.

· Organismal Systems > Digestive system > Gastric acid secretion.

· Organismal Systems > Digestive system > Pancreatic secretion.

· Organismal Systems > Digestive system > Carbohydrate digestion and absorption.

· Organismal Systems > Digestive system > Protein digestion and absorption.

· Organismal Systems > Digestive system > Mineral absorption.

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