SFRS7 Antibody - #DF4544

>>520•爱科研 进行中>>
(3)  
产品: SFRS7 抗体
货号: DF4544
描述: Rabbit polyclonal antibody to SFRS7
应用: WB IHC IF/ICC
反应: Human, Mouse
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 35 KD; 27kD(Calculated).
蛋白号: Q16629
RRID: AB_2836895

浏览相似产品>>

   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

联系销售
相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(94%), Xenopus(94%)
克隆:
Polyclonal
特异性:
SFRS7 Antibody detects endogenous levels of total SFRS7.
RRID:
AB_2836895
引用格式: Affinity Biosciences Cat# DF4544, RRID:AB_2836895.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

9G8; AAG3; arginine/serine-rich 7; HSSG1; RBM37; Serine/arginine-rich splicing factor 7; Splicing factor 9G8; Splicing factor; Splicing factor, arginine/serine rich 7; SRSF7; SRSF7_HUMAN; ZCCHC20; ZCRB2;

抗原和靶标

免疫原:
Uniprot:

Q16629(SRSF7_HUMAN) >>Visit HPA database.

基因/基因ID:
SRSF7(6432)
表达:
Q16629 SRSF7_HUMAN:

Brain, liver, kidney and lung.

序列:
MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPRRSASPERMD

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
94
Chicken
94
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q16629 作为底物

Site PTM Type Enzyme
Y4 Phosphorylation
Y7 Phosphorylation
K12 Sumoylation
K12 Ubiquitination
Y14 Phosphorylation
T20 Phosphorylation
K24 Acetylation
K24 Sumoylation
K24 Ubiquitination
S32 Phosphorylation
Y33 Phosphorylation
Y34 Phosphorylation
K70 Acetylation
K70 Ubiquitination
C73 S-Nitrosylation
R98 Methylation
R105 Methylation
Y107 Phosphorylation
K112 Acetylation
K112 Ubiquitination
Y117 Phosphorylation
S123 Phosphorylation
S155 Phosphorylation
S157 Phosphorylation
S159 Phosphorylation
S163 Phosphorylation
S165 Phosphorylation
S167 Phosphorylation
S171 Phosphorylation
S173 Phosphorylation
S175 Phosphorylation
S179 Phosphorylation
S181 Phosphorylation
S183 Phosphorylation
K185 Acetylation
S187 Phosphorylation
Y189 Phosphorylation
S192 Phosphorylation
S194 Phosphorylation
S196 Phosphorylation
S198 Phosphorylation
S200 Phosphorylation
S202 Phosphorylation
S204 Phosphorylation
S213 Phosphorylation
S215 Phosphorylation
S217 Phosphorylation
S221 Phosphorylation
S223 Phosphorylation
S225 Phosphorylation
S227 Phosphorylation
S231 Phosphorylation
S233 Phosphorylation
R236 Methylation

研究背景

功能:

Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.

翻译修饰:

Extensively phosphorylated on serine residues in the RS domain.

细胞定位:

Nucleus. Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Brain, liver, kidney and lung.

亚基结构:

Found in large molecular weight complexes containing CCNL1 and the p110 isoforms of either CDC2L1 or CDC2L2. Interacts with CCNL2 and CPSF6. Interacts with NXF1.

蛋白家族:

Belongs to the splicing factor SR family.

研究领域

· Genetic Information Processing > Transcription > Spliceosome.

· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.

限制条款

产品的规格、报价、验证数据请以官网为准，官网链接：www.affbiotech.com | www.affbiotech.cn（简体中文）| www.affbiotech.jp（日本語）

产品的数据信息为Affinity所有，未经授权不得收集Affinity官网数据或资料用于商业用途，对抄袭产品数据的行为我们将保留诉诸法律的权利。

产品相关数据会因产品批次、产品检测情况随时调整，如您已订购该产品，请以订购时随货说明书为准，否则请以官网内容为准，官网内容有改动时恕不另行通知。

Affinity保证所销售产品均经过严格质量检测。如您购买的商品在规定时间内出现问题需要售后时，请您在Affinity官方渠道提交售后申请。

产品仅供科学研究使用。不用于诊断和治疗。 

产品未经授权不得转售。

Affinity Biosciences将不会对在使用我们的产品时可能发生的专利侵权或其他侵权行为负责。Affinity Biosciences, Affinity Biosciences标志和所有其他商标所有权归Affinity Biosciences LTD.