ZADH1 Antibody - #DF4639

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产品: ZADH1 抗体
货号: DF4639
描述: Rabbit polyclonal antibody to ZADH1
应用: WB IHC IF/ICC
反应: Human, Rat
预测: Bovine, Sheep
分子量: 35 KD; 38kD(Calculated).
蛋白号: Q8N8N7
RRID: AB_2836930

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Rat
预测:
Bovine(80%), Sheep(80%)
克隆:
Polyclonal
特异性:
ZADH1 Antibody detects endogenous levels of total ZADH1.
RRID:
AB_2836930
引用格式: Affinity Biosciences Cat# DF4639, RRID:AB_2836930.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

15 oxoprostaglandin 13 reductase; 15 oxoprostaglandin delta 13 reductase; 15-oxoprostaglandin 13-reductase; DKFZp686P10120; FLJ39091; FLJ99229; PGR 2; PGR2; PRG-2; Prostaglandin reductase 2; PTGR 2; PTGR2; PTGR2_HUMAN; Zinc binding alcohol dehydrogenase domain containing 1; Zinc binding alcohol dehydrogenase domain containing protein 1; Zinc-binding alcohol dehydrogenase domain-containing protein 1;

抗原和靶标

免疫原:
Uniprot:

Q8N8N7(PTGR2_HUMAN) >>Visit HPA database.

基因/基因ID:
PTGR2(145482)
表达:
Q8N8N7 PTGR2_HUMAN:

Widely expressed.

序列:
MIVQRVVLNSRPGKNGNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDTGTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQLVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTVISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGILQLSQWFKEGKLKIKETVINGLENMGAAFQSMMTGGNIGKQIVCISEEISL

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Bovine
80
Sheep
80
Pig
70
Dog
70
Chicken
70
Rabbit
70
Horse
0
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q8N8N7 作为底物

Site PTM Type Enzyme
K14 Ubiquitination
Y29 Phosphorylation
Y51 Phosphorylation
S270 Phosphorylation
Y292 Phosphorylation

研究背景

功能:

Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation (By similarity).

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Widely expressed.

亚基结构:

Monomer.

蛋白家族:

Belongs to the NADP-dependent oxidoreductase L4BD family.

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