| 产品: | TAF3 抗体 |
| 货号: | DF4575 |
| 描述: | Rabbit polyclonal antibody to TAF3 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Zebrafish, Bovine, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 100 KD; 104kD(Calculated). |
| 蛋白号: | Q5VWG9 |
| RRID: | AB_2836939 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4575, RRID:AB_2836939.
展开/折叠
140 kDa TATA box-binding protein-associated factor; Bip2 protein; RNA polymerase II transcription factor TAFII140; TAF(II)140; TAF140; TAF3; TAF3 RNA polymerase II TATA box binding protein (TBP)-associated factor; TAF3_HUMAN; TAFII-140; TAFII140; TAFII155 protein; TATA box binding protein associated factor 3; TBP-associated factor 3; Transcription initiation factor TFIID 140 kDa subunit; Transcription initiation factor TFIID subunit 3;
抗原和靶标
- Q5VWG9 TAF3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDDVGEAFQLMGVSLHELEDYIHNIEPVTFPHQIPSFPVSKNNVLQFPQPGSKDAEERKEYIPDYLPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDELEEEEIINDENFLGKRPLDSPEAEELPAMKRPRLLSTKGDTLDVVLLEAREPLSSINTQKIPPMLSPVHVQDSTDLAPPSPEPPMLAPVAKSQMPTAKPLETKSFTPKTKTKTSSPGQKTKSPKTAQSPAMVGSPIRSPKTVSKEKKSPGRSKSPKSPKSPKVTTHIPQTPVRPETPNRTPSATLSEKISKETIQVKQIQTPPDAGKLNSENQPKKAVVADKTIEASIDAVIARACAEREPDPFEFSSGSESEGDIFTSPKRISGPECTTPKASTSANNFTKSGSTPLPLSGGTSSSDNSWTMDASIDEVVRKAKLGTPSNMPPNFPYISSPSVSPPTPEPLHKVYEEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIKVEPVALAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPAPSQNRPKTPPPAPAPAPGPMLVSPAPVPLPLLAQAAAGPALLPSPGPAASGASAKAPVRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDDCDDWYHWPCVGIMTAPPEEMQWFCPKCANKKKDKKHKKRKHRAH
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q5VWG9 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y52 | Phosphorylation | Uniprot | |
| Y56 | Phosphorylation | Uniprot | |
| S114 | Phosphorylation | Uniprot | |
| S183 | Phosphorylation | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| T200 | Phosphorylation | Uniprot | |
| T204 | Phosphorylation | Uniprot | |
| S229 | Phosphorylation | Uniprot | |
| S236 | Phosphorylation | Uniprot | |
| T237 | Phosphorylation | Uniprot | |
| S243 | Phosphorylation | Uniprot | |
| K261 | Acetylation | Uniprot | |
| T265 | Phosphorylation | Uniprot | |
| K266 | Acetylation | Uniprot | |
| S267 | Phosphorylation | Uniprot | |
| T269 | Phosphorylation | Uniprot | |
| T288 | Phosphorylation | Uniprot | |
| S291 | Phosphorylation | Uniprot | |
| S297 | Phosphorylation | Uniprot | |
| S301 | Phosphorylation | Uniprot | |
| S315 | Phosphorylation | Uniprot | |
| S317 | Phosphorylation | Uniprot | |
| S320 | Phosphorylation | Uniprot | |
| S323 | Phosphorylation | Uniprot | |
| T333 | Phosphorylation | Uniprot | |
| T339 | Phosphorylation | Uniprot | |
| T343 | Phosphorylation | Uniprot | |
| T347 | Phosphorylation | Uniprot | |
| S349 | Phosphorylation | Uniprot | |
| T364 | Phosphorylation | Uniprot | |
| K370 | Ubiquitination | Uniprot | |
| S373 | Phosphorylation | Uniprot | |
| S410 | Phosphorylation | Uniprot | |
| S411 | Phosphorylation | Uniprot | |
| S413 | Phosphorylation | Uniprot | |
| S415 | Phosphorylation | Uniprot | |
| S427 | Phosphorylation | Uniprot | |
| T432 | Phosphorylation | Uniprot | |
| T433 | Phosphorylation | Uniprot | |
| S483 | Phosphorylation | Uniprot | |
| Y491 | Phosphorylation | Uniprot | |
| S493 | Phosphorylation | Uniprot | |
| S494 | Phosphorylation | Uniprot | |
| S496 | Phosphorylation | Uniprot | |
| S498 | Phosphorylation | Uniprot | |
| T501 | Phosphorylation | Uniprot | |
| S517 | Phosphorylation | Uniprot | |
| S518 | Phosphorylation | Uniprot | |
| T568 | Phosphorylation | Uniprot | |
| T572 | Phosphorylation | Uniprot | |
| K601 | Acetylation | Uniprot | |
| K621 | Acetylation | Uniprot | |
| K625 | Acetylation | Uniprot | |
| K628 | Acetylation | Uniprot | |
| S667 | Phosphorylation | Uniprot | |
| K746 | Sumoylation | Uniprot | |
| S755 | Phosphorylation | Uniprot | |
| T762 | Phosphorylation | Uniprot | |
| K776 | Acetylation | Uniprot | |
| T794 | Phosphorylation | Uniprot | |
| S809 | Phosphorylation | Uniprot |
研究背景
Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.
Nucleus.
Belongs to the TFIID complex which is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Interacts with TAF10 via the histone fold. Interacts with TAF13, TBP, SAP130 and GCN5L2. Interacts with TBPL2.
The PHD-type zinc finger mediates binding to histone H3 methyllysine at position 4 (H3K4me3).
Belongs to the TAF3 family.
研究领域
· Genetic Information Processing > Transcription > Basal transcription factors.
· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.
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