| 产品: | EIF2B4 抗体 |
| 货号: | DF4577 |
| 描述: | Rabbit polyclonal antibody to EIF2B4 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 57 KD; 58kD(Calculated). |
| 蛋白号: | Q9UI10 |
| RRID: | AB_2836941 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4577, RRID:AB_2836941.
展开/折叠
EI2BD_HUMAN; EIF 2B; eIF 2B GDP GTP exchange factor subunit delta; eIF-2B GDP-GTP exchange factor subunit delta; Eif2b4; EIF2Bdelta; eukaryotic translation initiation factor 2B subunit 4; Translation initiation factor eIF-2B subunit delta;
抗原和靶标
- Q9UI10 EI2BD_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9UI10 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| S12 | Phosphorylation | Uniprot | |
| C69 | S-Nitrosylation | Uniprot | |
| T86 | Phosphorylation | Uniprot | |
| S130 | Phosphorylation | Uniprot | |
| T137 | Phosphorylation | Uniprot | |
| K142 | Ubiquitination | Uniprot | |
| Y147 | Phosphorylation | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| Y186 | Phosphorylation | Uniprot | |
| S187 | Phosphorylation | Uniprot | |
| S191 | Phosphorylation | Uniprot | |
| Y214 | Phosphorylation | Uniprot | |
| K282 | Ubiquitination | Uniprot | |
| K291 | Ubiquitination | Uniprot | |
| K297 | Ubiquitination | Uniprot | |
| S328 | Phosphorylation | Uniprot | |
| S340 | Phosphorylation | Uniprot | |
| R374 | Methylation | Uniprot | |
| S384 | Phosphorylation | Uniprot | |
| Y385 | Phosphorylation | Uniprot | |
| S399 | Phosphorylation | Uniprot | |
| K442 | Ubiquitination | Uniprot | |
| C465 | S-Nitrosylation | Uniprot | |
| K466 | Acetylation | Uniprot | |
| K466 | Ubiquitination | Uniprot |
研究背景
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
Complex of five different subunits; alpha, beta, gamma, delta and epsilon.
Belongs to the eIF-2B alpha/beta/delta subunits family.
研究领域
· Genetic Information Processing > Translation > RNA transport.
限制条款
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