| 产品: | EIF2B3 抗体 |
| 货号: | DF4578 |
| 描述: | Rabbit polyclonal antibody to EIF2B3 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 50 KD; 50kD(Calculated). |
| 蛋白号: | Q9NR50 |
| RRID: | AB_2836942 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4578, RRID:AB_2836942.
展开/折叠
EI2BG_HUMAN; EIF 2B; eIF 2B GDP GTP exchange factor subunit gamma; eIF-2B GDP-GTP exchange factor subunit gamma; eIF2B-gamma; Eif2b3; EIF2Bgamma; Eukaryotic translation initiation factor 2B subunit 3 gamma; Eukaryotic translation initiation factor 2B, gamma; eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa; OTTHUMP00000010262; OTTHUMP00000010263; Translation initiation factor eIF-2B subunit gamma;
抗原和靶标
- Q9NR50 EI2BG_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVGNDQLMEI
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9NR50 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| K61 | Ubiquitination | Uniprot | |
| K68 | Ubiquitination | Uniprot | |
| K72 | Ubiquitination | Uniprot | |
| Y92 | Phosphorylation | Uniprot | |
| K96 | Ubiquitination | Uniprot | |
| K134 | Methylation | Uniprot | |
| K134 | Ubiquitination | Uniprot | |
| K146 | Ubiquitination | Uniprot | |
| K148 | Methylation | Uniprot | |
| K165 | Ubiquitination | Uniprot | |
| K189 | Ubiquitination | Uniprot | |
| S220 | Phosphorylation | Uniprot | |
| K235 | Ubiquitination | Uniprot | |
| K259 | Ubiquitination | Uniprot | |
| S260 | Phosphorylation | Uniprot | |
| Y264 | Phosphorylation | Uniprot | |
| S265 | Phosphorylation | Uniprot | |
| K268 | Ubiquitination | Uniprot | |
| S314 | Phosphorylation | Uniprot | |
| K328 | Ubiquitination | Uniprot | |
| K349 | Ubiquitination | Uniprot | |
| K367 | Ubiquitination | Uniprot | |
| K382 | Ubiquitination | Uniprot | |
| K422 | Ubiquitination | Uniprot | |
| S428 | Phosphorylation | Uniprot |
研究背景
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
Complex of five different subunits; alpha, beta, gamma, delta and epsilon.
Belongs to the eIF-2B gamma/epsilon subunits family.
研究领域
· Genetic Information Processing > Translation > RNA transport.
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