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| 产品: | VANGL1 抗体 |
| 货号: | DF4607 |
| 描述: | Rabbit polyclonal antibody to VANGL1 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 50 KD; 60kD(Calculated). |
| 蛋白号: | Q8TAA9 |
| RRID: | AB_2836971 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4607, RRID:AB_2836971.
展开/折叠
ANGL planar cell polarity protein 1; KAI1 C-terminal interacting tetraspanin; KITENIN; Loop tail protein 2 homolog; Loop-tail protein 2 homolog; LPP2; MGC5338; STB2; STBM2; Strabismus 2; Strabismus, Drosophila, homolog of, 2; Van Gogh like protein 1; Van Gogh, Drosophila, homolog of, 1; Van Gogh-like protein 1; Vang like 1 (van gogh, Drosophila); Vang like protein 1; Vang-like 1; Vang-like protein 1; VANG1_HUMAN; VANGL 1; Vangl1;
抗原和靶标
According to PubMed:11956595, ubiquitously expressed. According to PubMed:12011995, expressed specifically in testis and ovary.
- Q8TAA9 VANG1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDTESTYSGYSYYSSHSKKSHRQGERTRERHKSPRNKDGRGSEKSVTIQPPTGEPLLGNDSTRTEEVQDDNWGETTTAITGTSEHSISQEDIARISKDMEDSVGLDCKRYLGLTVASFLGLLVFLTPIAFILLPPILWRDELEPCGTICEGLFISMAFKLLILLIGTWALFFRKRRADMPRVFVFRALLLVLIFLFVVSYWLFYGVRILDSRDRNYQGIVQYAVSLVDALLFIHYLAIVLLELRQLQPMFTLQVVRSTDGESRFYSLGHLSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNVDGPSNNATGQSRAMIAAAARRRDSSHNELYYEEAEHERRVKKRKARLVVAVEEAFIHIQRLQAEEQQKAPGEVMDPREAAQAIFPSMARALQKYLRITRQQNYHSMESILQHLAFCITNGMTPKAFLERYLSAGPTLQYDKDRWLSTQWRLVSDEAVTNGLRDGIVFVLKCLDFSLVVNVKKIPFIILSEEFIDPKSHKFVLRLQSETSV
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q8TAA9 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y7 | Phosphorylation | Uniprot | |
| Y13 | Phosphorylation | Uniprot | |
| S17 | Phosphorylation | Uniprot | |
| S20 | Phosphorylation | Uniprot | |
| S42 | Phosphorylation | Uniprot | |
| K44 | Ubiquitination | Uniprot | |
| S45 | Phosphorylation | Uniprot | |
| T52 | Phosphorylation | Uniprot | |
| S83 | Phosphorylation | Uniprot | |
| S86 | Phosphorylation | Uniprot | |
| S88 | Phosphorylation | Uniprot | |
| S96 | Phosphorylation | Uniprot | |
| K97 | Ubiquitination | Uniprot | |
| T288 | Phosphorylation | Uniprot | |
| Y290 | Phosphorylation | Uniprot | |
| T296 | Phosphorylation | Uniprot | |
| K299 | Ubiquitination | Uniprot | |
| K304 | Ubiquitination | Uniprot | |
| K310 | Acetylation | Uniprot | |
| K310 | Ubiquitination | Uniprot | |
| Y312 | Phosphorylation | Uniprot | |
| S325 | Phosphorylation | Uniprot | |
| S338 | Phosphorylation | Uniprot | |
| S339 | Phosphorylation | Uniprot | |
| Y344 | Phosphorylation | Uniprot | |
| Y345 | Phosphorylation | Uniprot | |
| K382 | Ubiquitination | Uniprot | |
| K407 | Ubiquitination | Uniprot | |
| K455 | Ubiquitination | Uniprot | |
| K513 | Ubiquitination | Uniprot | |
| S520 | Phosphorylation | Uniprot | |
| T522 | Phosphorylation | Uniprot | |
| S523 | Phosphorylation | Uniprot |
研究背景
Cell membrane>Multi-pass membrane protein.
According to ubiquitously expressed. According to expressed specifically in testis and ovary.
Heterodimer with VANGL2. Interacts through its C-terminal region with the N-terminal half of DVL1, DVL2 and DVL3. The PDZ domain of DVL1, DVL2 and DVL3 is required for the interaction (By similarity).
Belongs to the Vang family.
研究领域
· Environmental Information Processing > Signal transduction > Wnt signaling pathway. (View pathway)
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