(2)
(3)
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4653, RRID:AB_2837004.
展开/折叠
Barth syndrome; Cardiomyopathy dilated 3A (X linked); EFE2; Endocardial fibroelastosis 2; Protein G4.5; Tafazzin; TAZ; TAZ protein; TAZ_HUMAN;
抗原和靶标
High levels in cardiac and skeletal muscle. Up to 10 isoforms can be present in different amounts in different tissues. Most isoforms are ubiquitous. Isoforms that lack the N-terminus are found in leukocytes and fibroblasts, but not in heart and skeletal muscle. Some forms appear restricted to cardiac and skeletal muscle or to leukocytes.
- Q16635 TAZ_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCRGAEFFQAENEGKGVLDTGRHMPGAGKRREKGDGVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR
翻译修饰 - Q16635 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K56 | Ubiquitination | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| K149 | Acetylation | Uniprot | |
| K160 | Ubiquitination | Uniprot | |
| K264 | Ubiquitination | Uniprot |
研究背景
Some isoforms may be involved in cardiolipin (CL) metabolism.
Membrane>Single-pass membrane protein.
Cytoplasm.
Membrane>Single-pass membrane protein.
Membrane>Single-pass membrane protein.
Membrane>Single-pass membrane protein.
Cytoplasm.
Membrane>Single-pass membrane protein.
Cytoplasm.
Cytoplasm.
High levels in cardiac and skeletal muscle. Up to 10 isoforms can be present in different amounts in different tissues. Most isoforms are ubiquitous. Isoforms that lack the N-terminus are found in leukocytes and fibroblasts, but not in heart and skeletal muscle. Some forms appear restricted to cardiac and skeletal muscle or to leukocytes.
The hydrophilic domain may serve as an exposed loop interacting with other proteins.
Belongs to the taffazin family.
研究领域
· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.
文献引用
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