| 产品: | FEV 抗体 |
| 货号: | DF4675 |
| 描述: | Rabbit polyclonal antibody to FEV |
| 应用: | WB IF/ICC |
| 反应: | Human |
| 预测: | Pig, Bovine, Horse, Sheep, Chicken |
| 分子量: | 25 KD; 25kD(Calculated). |
| 蛋白号: | Q99581 |
| RRID: | AB_2837026 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4675, RRID:AB_2837026.
展开/折叠
ETS-domain transcription factor; FEV (ETS oncogene family); FEV; FEV ETS transcription factor; FEV_HUMAN; Fifth Ewing sarcoma variant; Fifth Ewing variant protein; HSRNAFEV; mPet1; PC12 ETS domain-containing transcription factor 1; PC12 ETS factor 1; Pet-1; Protein FEV;
抗原和靶标
In brain, exclusively expressed in the major serotonergic neurons of the dorsal and median raphe nuclei located in the midbrain and pons. Also detected in prostate and small intestine.
- Q99581 FEV_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRQSGASQPLLINMYLPDPVGDGLFKDGKNPSWGPLSPAVQKGSGQIQLWQFLLELLADRANAGCIAWEGGHGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMSKVHGKRYAYRFDFQGLAQACQPPPAHAHAAAAAAAAAAAAQDGALYKLPAGLAPLPFPGLSKLNLMAASAGVAPAGFSYWPGPGPAATAAAATAALYPSPSLQPPPGPFGAVAAASHLGGHYH
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q99581 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K91 | Ubiquitination | Uniprot | |
| Y98 | Phosphorylation | Uniprot | |
| K100 | Ubiquitination | Uniprot |
研究背景
Functions as a transcriptional regulator. According to it functions as a transcriptional repressor. Functions in the differentiation and the maintenance of the central serotonergic neurons. May play a role in cell growth.
Nucleus.
In brain, exclusively expressed in the major serotonergic neurons of the dorsal and median raphe nuclei located in the midbrain and pons. Also detected in prostate and small intestine.
Belongs to the ETS family.
研究领域
· Human Diseases > Cancers: Overview > Transcriptional misregulation in cancer.
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