产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4691, RRID:AB_2837042.
展开/折叠
Antigen NY-CO-28; CGI 52; MGC14401; NY CO 28; PCTL_HUMAN; PCTP-L; PCTP-like protein; PCTP2; SDCCAG28; Serologically defined colon cancer antigen 28; StAR related lipid transfer (START) domain containing 10; StAR-related lipid transfer protein 10; StARD10; START domain containing 10; START domain-containing protein 10;
抗原和靶标
- Q9Y365 STA10_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEKLAASTEPQGPRPVLGRESVQVPDDQDFRSFRSECEAEVGWNLTYSRAGVSVWVQAVEMDRTLHKIKCRMECCDVPAETLYDVLHDIEYRKKWDSNVIETFDIARLTVNADVGYYSWRCPKPLKNRDVITLRSWLPMGADYIIMNYSVKHPKYPPRKDLVRAVSIQTGYLIQSTGPKSCVITYLAQVDPKGSLPKWVVNKSSQFLAPKAMKKMYKACLKYPEWKQKHLPHFKPWLHPEQSPLPSLALSELSVQHADSLENIDESAVAESREERMGGAGGEGSDDDTSLT
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9Y365 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| S7 | Phosphorylation | Uniprot | |
| S21 | Phosphorylation | Uniprot | |
| S97 | Phosphorylation | Uniprot | |
| Y143 | Phosphorylation | Uniprot | |
| Y148 | Phosphorylation | Uniprot | |
| Y155 | Phosphorylation | Uniprot | |
| S166 | Phosphorylation | Uniprot | |
| S203 | Phosphorylation | Uniprot | |
| S253 | Phosphorylation | Uniprot | |
| S259 | Phosphorylation | Uniprot | |
| S284 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
| T288 | Phosphorylation | Uniprot | |
| S289 | Phosphorylation | Uniprot | |
| T291 | Phosphorylation | Uniprot |
研究背景
May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1 or 18:2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes.
Phosphorylation at Ser-284 by CK2 negatively regulates lipid transfer activity, possibly by decreasing membrane association.
Cell projection>Cilium>Flagellum. Cytoplasm. Membrane.
Note: In testis was predominantly detected at the flagella of elongated spermatids, with a strong signal also found at the tail of epididymal sperm (By similarity). Mainly cytosolic.
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