| 产品: | IL18BP 抗体 |
| 货号: | DF4709 |
| 描述: | Rabbit polyclonal antibody to IL18BP |
| 应用: | WB IF/ICC |
| 反应: | Human, Rat |
| 分子量: | 44 KD; 21kD(Calculated). |
| 蛋白号: | O95998 |
| RRID: | AB_2837060 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4709, RRID:AB_2837060.
展开/折叠
I18BP_HUMAN; IL-18BP; IL18 BP; IL18 BPa; IL18BP; IL18BPa; Interleukin 18 binding protein; Interleukin-18-binding protein; MC51L 53L 54L homolog gene product; Tadekinig alfa; Tadekinig-alfa;
抗原和靶标
A synthesized peptide derived from human IL18BP, corresponding to a region within C-terminal amino acids.
- O95998 I18BP_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTMRHNWTPDLSPLWVLLLCAHVVTLLVRATPVSQTTTAATASVRSTKDPCPSQPPVFPAAKQCPALEVTWPEVEVPLNGTLSLSCVACSRFPNFSILYWLGNGSFIEHLPGRLWEGSTSRERGSTGTQLCKALVLEQLTPALHSTNFSCVLVDPEQVVQRHVVLAQLWAGLRATLPPTQEALPSSHSSPQQQG
翻译修饰 - O95998 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T31 | Phosphorylation | Uniprot | |
| S34 | Phosphorylation | Uniprot | |
| S46 | O-Glycosylation | Uniprot | |
| T47 | O-Glycosylation | Uniprot | |
| S53 | O-Glycosylation | Uniprot | |
| N103 | N-Glycosylation | Uniprot | |
| N147 | N-Glycosylation | Uniprot |
研究背景
Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.
N- and O-glycosylated. O-glycosylated with core 1-like and core 2-like glycans. O-glycan heterogeneity at Ser-53: HexHexNAc (major) and Hex2HexNAc2 (minor). N-glycan heterogeneity at Asn-103: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major) and Hex6HexNAc5 (minor); N-glycan at Asn-147: dHex1Hex5HexNAc4.
Secreted.
Strongly expressed in heart, lung, placenta and spleen.
限制条款
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