产品: MYL6 抗体
货号: DF4718
描述: Rabbit polyclonal antibody to MYL6
应用: WB IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit
分子量: 17 KD; 17kD(Calculated).
蛋白号: P60660
RRID: AB_2837069

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%)
克隆:
Polyclonal
特异性:
MYL6 Antibody detects endogenous levels of total MYL6.
RRID:
AB_2837069
引用格式: Affinity Biosciences Cat# DF4718, RRID:AB_2837069.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

adult 1; MYH1; MYH1_HUMAN; MYH2; MYH3; MYH4; MYH6; MyHC-2x; MyHC-IIx/d; MYL1; MYL2; MYL3; MYL5; MYL6; Myosin light chain 2 regulatory cardiac slow; Myosin 1; Myosin heavy chain 1; Myosin heavy chain 1 skeletal muscle adult; Myosin heavy chain 2 skeletal muscle adult; Myosin heavy chain 2x; Myosin heavy chain 3 skeletal muscle adult; Myosin heavy chain 4 skeletal muscle adult; Myosin heavy chain 6 skeletal muscle adult; Myosin heavy chain; Myosin heavy chain IIx/d; Myosin heavy chain skeletal muscle adult 1; Myosin II; Myosin light chain 1 alkali skeletal fast; Myosin light chain 3 alkali ventricular skeletal slow; Myosin light chain 4 alkali atrial embryonic; Myosin light chain 5 regulatory; Myosin light chain 6 alkali smooth muscle and non muscle; Myosin-1; Myosin1; skeletal muscle;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
序列:
MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEAFVRHILSG

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Rabbit
100
Zebrafish
75
Chicken
75
Dog
0
Xenopus
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P60660 作为底物

Site PTM Type Enzyme
C2 Acetylation
K13 Ubiquitination
S20 Phosphorylation
R21 Methylation
T22 Phosphorylation
K26 Acetylation
K26 Ubiquitination
Y29 Phosphorylation
S30 Phosphorylation
T44 Phosphorylation
K50 Acetylation
K50 Ubiquitination
K56 Sumoylation
K56 Ubiquitination
S57 Phosphorylation
K63 Ubiquitination
K79 Ubiquitination
K81 Acetylation
K81 Ubiquitination
T85 Phosphorylation
Y86 Phosphorylation
Y89 Phosphorylation
R94 Methylation
K98 Acetylation
K98 Ubiquitination
T103 Phosphorylation
T115 Phosphorylation
T121 Phosphorylation
S135 Phosphorylation
Y141 Phosphorylation

研究背景

功能:

Regulatory light chain of myosin. Does not bind calcium.

亚基结构:

Myosin is a hexamer of 2 heavy chains and 4 light chains. Interacts with SPATA6.

研究领域

· Cellular Processes > Cellular community - eukaryotes > Tight junction.   (View pathway)

· Organismal Systems > Circulatory system > Vascular smooth muscle contraction.   (View pathway)

· Organismal Systems > Endocrine system > Oxytocin signaling pathway.

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